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    1-Hydroxypinoresinol 1-O-glucoside
    1-Hydroxypinoresinol 1-O-glucoside
    Information
    CAS No. 81495-71-8 Price
    Catalog No.CFN96713Purity>=98%
    Molecular Weight536.53Type of CompoundLignans
    FormulaC26H32O12Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison
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    1-Hydroxypinoresinol 1-O-glucoside Description
    Source: The rhizomes of Salvia miltiorrhiza.
    Biological Activity or Inhibitors: 1. (+)-1-Hydroxypinoresinol 1-O-beta-D-glucoside exhibits peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of 3.23 +/- 0.04, 2.26 +/- 0.07 and 32.3 +/- 0.13 microM, respectively.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8638 mL 9.3191 mL 18.6383 mL 37.2766 mL 46.5957 mL
    5 mM 0.3728 mL 1.8638 mL 3.7277 mL 7.4553 mL 9.3191 mL
    10 mM 0.1864 mL 0.9319 mL 1.8638 mL 3.7277 mL 4.6596 mL
    50 mM 0.0373 mL 0.1864 mL 0.3728 mL 0.7455 mL 0.9319 mL
    100 mM 0.0186 mL 0.0932 mL 0.1864 mL 0.3728 mL 0.466 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    1-Hydroxypinoresinol 1-O-glucoside References Information
    Citation [1]

    Arch Pharm Res. 2003 Jan;26(1):24-7.

    Further isolation of antioxidative (+)-1-hydroxypinoresinol-1-O-beta-D-glucoside from the rhizome of Salvia miltiorrhiza that acts on peroxynitrite, total ROS and 1,1-diphenyl-2-picrylhydrazyl radical.[Pubmed: 12568353]
    A furanofuranoid lignan glycoside, with radical scavenging on peroxynitrite, total reactive oxygen species (ROS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, was isolated from the rhizome of Salvia miltiorrhiza and characterized as (+)-1-hydroxypinoresinol-1-O-beta-D-glucoside(1-Hydroxypinoresinol 1-O-glucoside) based on spectroscopic evidence. The compound exhibited peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of 3.23 +/- 0.04, 2.26 +/- 0.07 and 32.3 +/- 0.13 microM, respectively. Penicillamine, Trolox (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) and L-ascorbic acid, acting as positive controls, showed radical scavenging activities with IC50 values of 6.72 +/- 0.25, 1.43 +/- 0.04 and 11.4 +/- 0.07 microM, respectively.