ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
More articles cited ChemFaces products.
Food Chem. 2017 Aug 1;Invest New Drugs. 2017 Apr;J Pharm Biomed Anal. 2017 Jun 5;Sci Rep. 2017 Aug 15;J Ethnopharmacol.2016 Jun 25.
Front Pharmacol. 2016 Nov 30Food Chem.2018 Jun 30;Int J Mol Sci. 2018 Jan 23;Universite de Bordeaux15 Dec 2017;Phytomedicine1 March 2018;
Phytomedicine.2018 Jan 1;J Chromatogr Sci.2015 Feb 5. pii: bmu231. Sci Rep. Jan. 2018J. of Pha. and Biomed. Analysis25 Jan. 2016
Our products had been exported to the following research institutions and universities, And still growing.
Colorado State University (USA)Kamphaengphet Rajabhat University (Thailand)Institute of Chinese Materia Med... (China)Copenhagen University (Denmark)
Chang Gung University (Taiwan)Osmania University (India)John Innes Centre (United Kingdom)Georgia Institute of Technology (USA)
University of Wuerzburg (Germany)Shanghai University of TCM (China)Leibniz-Institut für Pflanzenbi... (Germany)
||20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoal activity due to high cytotoxicity. |
||ROS | Antifection|
|Nat. Prod. Lett., 2002, 16(4):277-81. |
|Antioxidant capacity of abietanes from Sphacele salviae.[Pubmed: 12168765 ]|
METHODS AND RESULTS:
Carnosol 1, rosmanol 2, carnosic acid 3 and 20-Deoxocarnosol 4, the main phenolic abietanes present in aerial parts of the Chilean medicinal plant Sphacele salviae were tested for antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).
All compounds displayed higher antioxidant levels than BHT under the same conditions and carnosic acid was more efficient than vitamin E.
|Int. J. Mol. Sci., 2014, 15(5):8360-71. |
|In vitro antiprotozoal activity of abietane diterpenoids isolated from Plectranthus barbatus Andr.[Pubmed: 24823881 ]|
|Chromatographic separation of the n-hexane extract of the aerial part of Plectranthus barbatus led to the isolation of five abietane-type diterpenes: dehydroabietane (1); 5,6-didehydro-7-hydroxy-taxodone (2); taxodione (3); 20-Deoxocarnosol (4) and 6α,11,12,-trihydroxy-7β,20-epoxy-8,11,13-abietatriene (5). |
METHODS AND RESULTS:
The structures were determined using spectroscopic methods including one- and two-dimensional NMR methods. Compounds (1)-(3) and (5) are isolated here for the first time from the genus Plectranthus. The isolated abietane-type diterpenes tested in vitro for their antiprotozoal activity against erythrocytic schizonts of Plasmodium falciparum, intracellular amastigotes of Leishmania infantum and Trypanosoma cruzi and free trypomastigotes of T. brucei. Cytotoxicity was determined against fibroblast cell line MRC-5.
Compound (2) 5,6-didehydro-7-hydroxy-taxodone showed remarkable activity with acceptable selectivity against P. falciparum (IC50 9.2 μM, SI 10.4) and T. brucei (IC50 1.9 μM, SI 50.5). Compounds (3)-(5) exhibited non-specific antiprotozoal activity due to high cytotoxicity. Compound (1) dehydroabietane showed no antiprotozoal potential.
||The herbs of Salvia yunnanensis
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.