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    3,3'-Bilawsone
    3,3'-Bilawsone
    Information
    CAS No. 33440-64-1 Price
    Catalog No.CFN92932Purity>=98%
    Molecular Weight346.29Type of CompoundQuinones
    FormulaC20H10O6Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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  • Cancer Research Initatives Found... (Malaysia)
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    3,3'-Bilawsone Description
    Source: The herbs of Lomatia ferruginea
    Biological Activity or Inhibitors:
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8878 mL 14.4388 mL 28.8775 mL 57.7551 mL 72.1938 mL
    5 mM 0.5776 mL 2.8878 mL 5.7755 mL 11.551 mL 14.4388 mL
    10 mM 0.2888 mL 1.4439 mL 2.8878 mL 5.7755 mL 7.2194 mL
    50 mM 0.0578 mL 0.2888 mL 0.5776 mL 1.1551 mL 1.4439 mL
    100 mM 0.0289 mL 0.1444 mL 0.2888 mL 0.5776 mL 0.7219 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    3,3'-Bilawsone References Information
    Citation [1]

    Phytochem Anal. 2010 Sep-Oct;21(5):444-50.

    Simultaneous determination of three naphthoquinones in the leaves of Impatiens balsamina L. by reversed-phase high-performance liquid chromatography.[Pubmed: 20931623 ]
    Naphthoquinones; lawsone (1), lawsone methyl ether (2) and methylene-3,3'-Bilawsone (3) are the main active compounds of Impatiens balsamina leaves. OBJECTIVE: To develop and validate an HPLC method for simultaneous quantitative determination of 1-3 in I. balsamina leaf extracts. METHODOLOGY: The method utilised a Supelco® C(18) column (5 μm, 4.6 × 150 mm) at 25°C with the mixture of 2% aqueous acetic acid : methanol (gradient elution as follows: 0-10 min, 25 : 75; 10-20 min, 32 : 68; 20-35 min, 55 : 45) as the mobile phase at a flow-rate of 1 mL/min, and UV detection at 280 nm. The parameters of linearity, repeatability, reproducibility, accuracy specificity and sensitivity of the method were evaluated. RESULTS: The recovery of the method was 96-101% and linearity (r(2) ≥ 0.9995) was obtained for all naphthoquinones. A high degree of specificity, as well as repeatability and reproducibility (RSD less than 5%), were also achieved.