|Description:||1. 6'-O-Cinnamoylharpagide has anti-inflammatory activity. |
|Source:||The roots of Scrophularia ningpoensis Hemsl.|
|Solvent:||DMSO, Pyridine, Methanol, Ethanol, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.0223 mL||10.1114 mL||20.2229 mL||40.4457 mL||50.5571 mL|
|5 mM||0.4045 mL||2.0223 mL||4.0446 mL||8.0891 mL||10.1114 mL|
|10 mM||0.2022 mL||1.0111 mL||2.0223 mL||4.0446 mL||5.0557 mL|
|50 mM||0.0404 mL||0.2022 mL||0.4045 mL||0.8089 mL||1.0111 mL|
|100 mM||0.0202 mL||0.1011 mL||0.2022 mL||0.4045 mL||0.5056 mL|
Nat Prod Res. 2009;23(13):1181-8.
|A new iridoid glycoside from Scrophularia ningpoensis.[Pubmed: 19731136]|
|A new iridoid glycoside, named 6'-O-Cinnamoylharpagide (1), has been isolated from the roots of Scrophularia ningpoensis (Scrophulariaceae) together with nine known compounds, harpagide (2), harpagoside (3), 8-O-feruloylharpagide (4), 8-O-(p-coumaroyl)harpagide (5), 6-O-methylcatalpol (6), aucubin (7), buergerinin B (8), teuhircoside (9) and 6-O-cinnamoyl-D-glucopyranose (10). Compound 10 was obtained as an inseparable mixture of 6-O-cinnamoyl-alpha-D-glucopyranose and 6-O-cinnamoyl-beta-D-glucopyranose at a ratio of 1 : 1, which is presumably formed by cleavage of compound 1. Their structures were elucidated on the basis of chemical and spectral analysis.|
Planta Medica, 2012, 78(14).
|Compounds form the roots of Harpagophytum procumbens and their anti-inflammatory activity.[Reference: WebLink]|
|Six known compounds: cinnamic acid (1), harpagoside, (2), 8-O-(cis-cinnamoyl)harpagide (3), acteoside (4), isoacteoside (5), and 6'-O-Cinnamoylharpagide (6) were isolated from the roots of Harpagophytum procumbens. The chemical structures of these compounds were determined on the basis of spectroscopic analyses including 2D NMR. Their anti-inflammatory activity was evaluated against LPS-induced NO production in macrophage RAW264.7 cells. Fig.1 Fig.2|