• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    Aloeresin D
    Aloeresin D
    Information
    CAS No. 105317-67-7 Price $318 / 10mg
    Catalog No.CFN90717Purity>=98%
    Molecular Weight556.56Type of CompoundFlavonoids
    FormulaC29H32O11Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    Our products had been exported to the following research institutions and universities, And still growing.
  • Leibniz Institute of Plant Bioch... (Germany)
  • Auburn University (USA)
  • Kitasato University (Japan)
  • Universitas Airlangga (Indonesia)
  • Universidad Industrial de Santan... (Colombia)
  • Seoul National University of Sci... (Korea)
  • University of Hull (United Kingdom)
  • Colorado State University (USA)
  • Anna University (India)
  • Technical University of Denmark (Denmark)
  • VIT University (India)
  • More...
  • Package
    Featured Products
    Poncirin

    Catalog No: CFN90448
    CAS No: 14941-08-3
    Price: $218/20mg
    Sibiricose A5

    Catalog No: CFN90645
    CAS No: 107912-97-0
    Price: $138/20mg
    8,8''-Bibaicalein

    Catalog No: CFN95007
    CAS No: 135309-02-3
    Price: $418/5mg
    Xanthohumol

    Catalog No: CFN98958
    CAS No: 569-83-5
    Price: $60/20mg
    Isolinderalactone

    Catalog No: CFN99762
    CAS No: 957-66-4
    Price: $238/5mg
    Biological Activity
    Description: Aloeresin D is a natural product from Aloe arborescens Mill.
    Targets: BACE | Beta Amyloid
    In vitro:
    Planta Med. 2008 Apr;74(5):540-5.
    BACE1 (beta-secretase) inhibitory chromone glycosides from Aloe vera and Aloe nobilis.[Pubmed: 18543151]

    METHODS AND RESULTS:
    Four new chromone glycosides allo-Aloeresin D (2) , C-2'-decoumaroyl-aloeresin G (8), 2'-O-coumaroyl-(S)-aloesinol (9), 2'-O-[ P-methoxy-(E)-cinnamoyl]-(S)-aloesinol (10) and nine known chromone glycosides ( 1, 3 - 7, 11 - 13) were isolated from two Aloe spp. plants, A. vera and A. nobilis. Among them, 1 and 8 showed significant inhibitory activity against BACE1 (beta-secretase) with IC (50) values of 39.0 and 20.5 x 10 (-6) M, as well as inhibition of Abeta (1-42) production by 7.4 and 12.3 %, respectively, in B103 neuroblastoma cells at 30 ppm.
    CONCLUSIONS:
    The preliminary structure-activity relationships of ALOE chromone glucosides were also discussed.
    Aloeresin D Description
    Source: The herbs of Aloe arborescens Mill.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds
    Magnolignan A

    Catalog No: CFN96188
    CAS No: 93673-81-5
    Price: $388/5mg
    Methylnissolin

    Catalog No: CFN90838
    CAS No: 733-40-4
    Price: $388/10mg
    Irigenin

    Catalog No: CFN93276
    CAS No: 548-76-5
    Price: $238/20mg
    2-Hydroxy-3-methoxybenzoic acid gl...

    Catalog No: CFN89113
    CAS No: 172377-87-6
    Price: $268/5mg
    2-Cinnamoyl-1-galloylglucose

    Catalog No: CFN95098
    CAS No: 56994-83-3
    Price: $338/5mg
    Ganoderic acid C6

    Catalog No: CFN92290
    CAS No: 105742-76-5
    Price: $368/10mg
    Isololiolide

    Catalog No: CFN95106
    CAS No: 38274-00-9
    Price: $388/5mg
    Bruceine E

    Catalog No: CFN89340
    CAS No: 21586-90-3
    Price: $318/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7968 mL 8.9838 mL 17.9675 mL 35.935 mL 44.9188 mL
    5 mM 0.3594 mL 1.7968 mL 3.5935 mL 7.187 mL 8.9838 mL
    10 mM 0.1797 mL 0.8984 mL 1.7968 mL 3.5935 mL 4.4919 mL
    50 mM 0.0359 mL 0.1797 mL 0.3594 mL 0.7187 mL 0.8984 mL
    100 mM 0.018 mL 0.0898 mL 0.1797 mL 0.3594 mL 0.4492 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Phytochemistry Volume 25, Issue 9, 1986, Pages 2219-2222
    A C-glucosylated 5-methylchromone from Kenya aloe[Reference: WebLink]
    A new bitter C-glucoside, Aloeresin D, was isolated from a commercial sample of Kenya aloe. Its structure was assigned as 8-C-β-d-[2-O-(E)-p-coumaroyl]glucopyranosyl-2-[(R)-2-hydroxy]propyl-7-methoxy-5-methyl-chromone by spectral data and chemical transformations.