ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
J Nat Med.2017 Jul 5. Tropical J. of Pha. ResearchNo 3 (2017) Neuropharmacology.2018 Mar 15;Molecules. 2017 Dec 4;Kor. J. Pharmacogn.47(1):62-72(2016)
ScientificWorldJournal. 2014 Feb 9.Faculty of Chem. & Nat. Resource Eng.Jul. 2014Universite de Bordeaux15 Dec 2017;Phytomedicine1 March 2018;Mol Immunol. 2016 Oct;78:121-132.
Antiviral Res.2013 Jun;98(3):386-93.Int J Mol Sci. 2018 Jan 23;BMC Complement Altern Med.2017 Aug 9;Sci Rep. 2017 Jun 12;
Our products had been exported to the following research institutions and universities, And still growing.
Leibniz Institute of Plant Bioch... (Germany)Auburn University (USA)Kitasato University (Japan)Universitas Airlangga (Indonesia)
Universidad Industrial de Santan... (Colombia)Seoul National University of Sci... (Korea)University of Hull (United Kingdom)Colorado State University (USA)
Anna University (India)Technical University of Denmark (Denmark)VIT University (India)
|| Aloeresin D is a natural product from Aloe arborescens Mill.|
||BACE | Beta Amyloid|
|Planta Med. 2008 Apr;74(5):540-5. |
|BACE1 (beta-secretase) inhibitory chromone glycosides from Aloe vera and Aloe nobilis.[Pubmed: 18543151]|
METHODS AND RESULTS:
Four new chromone glycosides allo-Aloeresin D (2) , C-2'-decoumaroyl-aloeresin G (8), 2'-O-coumaroyl-(S)-aloesinol (9), 2'-O-[ P-methoxy-(E)-cinnamoyl]-(S)-aloesinol (10) and nine known chromone glycosides ( 1, 3 - 7, 11 - 13) were isolated from two Aloe spp. plants, A. vera and A. nobilis. Among them, 1 and 8 showed significant inhibitory activity against BACE1 (beta-secretase) with IC (50) values of 39.0 and 20.5 x 10 (-6) M, as well as inhibition of Abeta (1-42) production by 7.4 and 12.3 %, respectively, in B103 neuroblastoma cells at 30 ppm.
The preliminary structure-activity relationships of ALOE chromone glucosides were also discussed.
Aloeresin D Description
||The herbs of Aloe arborescens Mill.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Phytochemistry Volume 25, Issue 9, 1986, Pages 2219-2222 |
|A C-glucosylated 5-methylchromone from Kenya aloe[Reference: WebLink]|
|A new bitter C-glucoside, Aloeresin D, was isolated from a commercial sample of Kenya aloe. Its structure was assigned as 8-C-β-d-[2-O-(E)-p-coumaroyl]glucopyranosyl-2-[(R)-2-hydroxy]propyl-7-methoxy-5-methyl-chromone by spectral data and chemical transformations.|