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Bruceantinol A
Bruceantinol A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Bruceantinol A
Price: $398 / 5mg
CAS No.: 948038-36-6
Catalog No.: CFN91971
Molecular Formula: C29H36O13
Molecular Weight: 592.59 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The fruits of Brucea javanica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $457.7 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
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  • CSIRO - Agriculture Flagship (Australia)
  • Universidad Miguel Hernández (Spain)
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Biological Activity
Description: Bruceantinol A is a natural product from Brucea javanica.
In vitro:
J Nat Prod. 2007 Oct;70(10):1654-7.
Screening of Indonesian medicinal plant extracts for antibabesial activity and isolation of new quassinoids from Brucea javanica.[Pubmed: 17896817]
Boiled extracts derived from 28 Indonesian medicinal plants were screened for their antibabesial activity against Babesia gibsoni in vitro.
METHODS AND RESULTS:
Of these extracts, the fruit of Brucea javanica was the most active in inhibiting parasite growth at a concentration of 10 microg/mL. Bioassay-guided fractionation of the fruit extract of Br. javanica led to the isolation of two new quassinoids, bruceantinol B and bruceine J, and the structures of these compounds were elucidated on the basis of their spectroscopic data and by chemical transformation to known compounds. In addition, the known quassinoids bruceines A-D, bruceantinol, and yadanziolide A were isolated.
CONCLUSIONS:
Antibabesial activities were also examined in vitro, and bruceine A and bruceantinol were shown to be more potent than diminazene aceturate, a drug (IC50 = 103 ng/mL) used clinically against B. gibsoni, with IC50 values of 4 and 12 ng/mL, respectively.
Bruceantinol A Description
Source: The fruits of Brucea javanica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

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doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6875 mL 8.4375 mL 16.8751 mL 33.7501 mL 42.1877 mL
5 mM 0.3375 mL 1.6875 mL 3.375 mL 6.75 mL 8.4375 mL
10 mM 0.1688 mL 0.8438 mL 1.6875 mL 3.375 mL 4.2188 mL
50 mM 0.0338 mL 0.1688 mL 0.3375 mL 0.675 mL 0.8438 mL
100 mM 0.0169 mL 0.0844 mL 0.1688 mL 0.3375 mL 0.4219 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Poricoic acid A(F)

Catalog No: CFN92838
CAS No: 137551-38-3
Price: $218/20mg
Matrine

Catalog No: CFN98835
CAS No: 519-02-8
Price: $30/20mg
Syringetin

Catalog No: CFN70363
CAS No: 4423-37-4
Price: $ / mg
Santamarine

Catalog No: CFN98667
CAS No: 4290-13-5
Price: $ /
Methyl rosmarinate

Catalog No: CFN97567
CAS No: 99353-00-1
Price: $268/20mg
Kukoamine A

Catalog No: CFN93215
CAS No: 75288-96-9
Price: $ / mg
Rebaudioside C

Catalog No: CFN90258
CAS No: 63550-99-2
Price: $100/20mg
Neobavaisoflavone

Catalog No: CFN92222
CAS No: 41060-15-5
Price: $60/20mg
Rhodionin

Catalog No: CFN99758
CAS No: 85571-15-9
Price: $258/10mg
Apigenin

Catalog No: CFN98843
CAS No: 520-36-5
Price: $40/20mg
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