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Confluentic acid
Confluentic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Confluentic acid
Price:
CAS No.: 6009-12-7
Catalog No.: CFN97015
Molecular Formula: C28H36O8
Molecular Weight: 500.6 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Himatanthus sucuuba
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Confluentic acid shows selective inhibition of Monoamine oxidase B with IC50 value of 0.22 microM.
Targets: MAO
In vitro:
Chem Pharm Bull (Tokyo). 1994 Jun;42(6):1198-201.
Confluentic acid and 2'-O-methylperlatolic acid, monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.[Pubmed: 8069971]
Monoamine oxidase B (MAO-B) inhibitors were isolated from the bark of a Brazilian plant, Himatanthus sucuuba (SPR.).
METHODS AND RESULTS:
Assignments of the 1H- and 13C-NMR data using two dimensional (2D)-NMR techniques showed the active components to be known lichen depsides, Confluentic acid (1) and 2'-O-methylperlatolic acid (2).
METHODS AND RESULTS:
The depside (1) showed selective inhibition of MAO-B with IC50 value of 0.22 microM.
Confluentic acid Description
Source: The herbs of Himatanthus sucuuba
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9976 mL 9.988 mL 19.976 mL 39.9521 mL 49.9401 mL
5 mM 0.3995 mL 1.9976 mL 3.9952 mL 7.9904 mL 9.988 mL
10 mM 0.1998 mL 0.9988 mL 1.9976 mL 3.9952 mL 4.994 mL
50 mM 0.04 mL 0.1998 mL 0.3995 mL 0.799 mL 0.9988 mL
100 mM 0.02 mL 0.0999 mL 0.1998 mL 0.3995 mL 0.4994 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN90885Cytosporone B321661-62-5322.4C18H26O5
CFN986212'-O-Methylperlatolic acid38968-07-9458.6 C26H34O7
CFN97015Confluentic acid6009-12-7500.6 C28H36O8
CFN99352Bongardol123690-76-6544.9 C36H64O3
CFN960209-Deoxygoniopypyrone136685-37-5234.3C13H14O4
CFN96048Goniopypyrone129578-07-0250.3C13H14O5
CFN98507Ginkgolic acid C13:020261-38-5320.47C20H32O3
CFN90339Ginkgolic acid C15:016611-84-0348.52C22H36O3
CFN90161Ginkgolic acid C15:122910-60-7346.50C22H34O3
CFN98508Ginkgolic acid C17:1111047-30-4374.56C24H38O3
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