ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: firstname.lastname@example.org
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $214.4 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Mol Med Rep.2015, 12(5):7789-95Acta Biochim Pol.2015, 62(2):253-8Food Research International...2016...Evid Based Complement Alternat Me...2016...Sci Rep. 2017, 17332(7)Research on Crops.2017, 18(3):569Chin. Med.J.Res. Prac.2017, 31(4)Oncotarget.2017, 8(53):90925-90947
Malaysian J of Fundamental and Ap...2018...Mol Pharm.2018, 15(8):3285-3296Sci Rep. 2018, 1-9Evid Based Complement Alternat Me...2018...Evid Based Complement Alternat Me...2018...Cell Death Dis.2019, 10(12):882Neuropharmacology2019, 151437Int J Mol Sci.2019, 20(16):E4015
Life Sci.2019, 216:259-270Molecules.2019, 24(4):E744J Clin Med.2019, 8(10):E1664Antioxidants (Basel).2019, 8(8):E307Food Funct.2020, 10.1039Industrial Crops and Products...2020...J Mol Recognit.2020, 33(2):e2819
Our products had been exported to the following research institutions and universities, And still growing.
Mahatma Gandhi University (India)University of Oslo (Norway)University of Medicine and Phar... (Romania)University of Madras (India)
Wroclaw Medical University (Poland)Donald Danforth Plant Science C... (USA)Northeast Normal University Cha... (China)Universita' Degli Studi Di Cagl... (Italy)
Nicolaus Copernicus Uniwersity (Poland)Osmania University (India)University of Sao Paulo (Brazil)
Related Screening Libraries
||(+)-Cycloolivil has antioxidant activity, it may prevent thrombotic complications associated to platelet hyperaggregability and be the base for the development of antiaggregant therapeutic strategies.|
|Blood Cell. Mol. Dis., 2009, 42(3):279-85. |
|Olive tree wood phenolic compounds with human platelet antiaggregant properties.[Pubmed: 19195914]|
|Oleuropein and (+)-Cycloolivil are natural polyphenolic compounds with a significant radical scavenging activity present in olive tree. We have investigated the antiaggregant effects of oleuropein and (+)-Cycloolivil isolated from an ethyl acetate extract of olive tree wood.
METHODS AND RESULTS:
Oleuropein and (+)-Cycloolivil reduced the ability of thrombin to stimulate platelet aggregation. Both compounds reduced thrombin-evoked Ca(2+) release and entry to a similar extent to hydroxytyrosol. This effect was greater in platelets from patients with type 2 diabetes mellitus than in controls. Thrombin-, thapsigargin- and 2,5-di-(tert-butyl)-1,4-hydroquinone (TBHQ)-evoked protein tyrosine phosphorylation, which is involved in Ca(2+) signalling and platelet aggregation, is inhibited by oleuropein and (+)-Cycloolivil. oleuropein and (+)-Cycloolivil are natural oxygen radical scavengers that reduce thrombin-induced protein tyrosine phosphorylation, Ca(2+) signalling and platelet aggregation.
These observations suggest that oleuropein and (+)-Cycloolivil may prevent thrombotic complications associated to platelet hyperaggregability and be the base for the development of antiaggregant therapeutic strategies.
||The herbs of Maytenus hookeri Loes.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.