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Daphmacropodine
Daphmacropodine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Daphmacropodine
Price:
CAS No.: 39729-21-0
Catalog No.: CFN98629
Molecular Formula: C32H51NO4
Molecular Weight: 513.8 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The branches of Daphniphyllum macropodum Miq.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Daphmacropodine Description
Source: The branches of Daphniphyllum macropodum Miq.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9463 mL 9.7314 mL 19.4628 mL 38.9257 mL 48.6571 mL
5 mM 0.3893 mL 1.9463 mL 3.8926 mL 7.7851 mL 9.7314 mL
10 mM 0.1946 mL 0.9731 mL 1.9463 mL 3.8926 mL 4.8657 mL
50 mM 0.0389 mL 0.1946 mL 0.3893 mL 0.7785 mL 0.9731 mL
100 mM 0.0195 mL 0.0973 mL 0.1946 mL 0.3893 mL 0.4866 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chem Biodivers. 2007 Feb;4(2):129-38.
Secophnane-type alkaloids from Daphniphyllum oldhami.[Pubmed: 17311225]

METHODS AND RESULTS:
Four new alkaloids, daphnioldhanins D-G (1-4, resp.), together with five known alkaloids, Daphmacropodine (5), secodaphniphylline (6), deoxycalyciphylline B (7), deoxyisocalyciphylline B (8), and daphmanidin A (9), were isolated from the roots of Daphniphyllum oldhami. Their structures were elucidated on the basis of spectroscopic data and chemical methods.
CONCLUSIONS:
Compound 1 at 2.0 microM showed potent antioxidant activity against H(2)O(2)-induced impairment in PC12 cells.
CFN97484Daphnilongeridine922522-15-4513.8 C32H51NO4
CFN98003Daphmacrine19775-48-5511.8 C32H49NO4
CFN98270Daphnezomine B247078-43-9375.6 C23H37NO3
CFN98629Daphmacropodine39729-21-0513.8 C32H51NO4
CFN99061Yunnandaphninine G1042143-83-8469.7 C30H47NO3
CFN9928411-Hydroxycodaphniphylline1186496-68-3485.7 C30H47NO4
CFN99608Codaphniphylline14694-15-6469.7 C30H47NO3
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