| Structure Identification: |
| Journal of Food Composition & Analysis, 2015,42 :1-7. | | Hepatotoxic pyrrolizidine alkaloids in Emilia sonchifolia from Taiwan[Reference: WebLink] | Emilia sonchifolia (L.) DC. (Lilac tasselflower, Zi Bei Cao) is used in Asian countries for food or medicinal purposes. We have investigated the hepatotoxic pyrrolizidine alkaloids (PAs) contained in E. sonchifolia. The objective was to determine profile and quantity of the PAs in E. sonchifolia samples that were collected from several towns in Taiwan.
METHODS AND RESULTS:
Pyrrolizidine alkaloids were isolated and purified from the aqueous acid extracts by use of strong cation exchange-solid phase extraction (SCX-SPE). Alkaloid extracts were analyzed using gas–chromatography mass spectrometry (GC–MS). Eleven PAs of two types were identified in E. sonchifolia (by type): (1) retronecine bases, senecionine, seneciphylline and integerrimine; (2) otonecine bases, senkirkine, otosenine, neosenkirkine, petasitenine, acetylsenkirkine, Desacetyldoronine, acetylpetasitenine, and doronine.
CONCLUSIONS:
Quantification of the individual PAs was determined by six-point linear regression curves in the range of 25–400 μg/mL of senkirkine and senecionine. |
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