Glyurallin A | CAS:199331-36-7 | Manufacturer ChemFaces

Glyurallin A

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Glyurallin A possesses an antigenotoxic effect against carcinogenic N-methyl-N-nitrosourea (MNU) for the first time, it is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.

In vitro:

Genes Environ. 2017 Jan 6;39:5.

Isolation and characterization of antimutagenic components of Glycyrrhiza aspera against N-methyl-N-nitrosourea.[Pubmed: 28074112 ]

A powdered ethanolic extract of Glycyrrhiza aspera root exhibits antimutagenic activity against N-methyl-N-nitrosourea (MNU) based on the Ames assay with Salmonella typhimurium TA1535. The aim of this study was to identify the antimutagenic components of the powdered ethanolic extract of G. aspera root.
METHODS AND RESULTS:
The powdered ethanolic extract of G. aspera root was sequentially suspended in n-hexane, carbon tetrachloride, dichloromethane, ethyl acetate, and ethanol, and each solvent soluble fraction and the residue were assayed for antimutagenic activity against MNU in S. typhimurium TA1535. The dichloromethane soluble fraction exhibited the highest antimutagenicity and was fractionated several times by silica gel chromatography. The fraction with the highest antimutagenic activity was further purified using HPLC, and the fractions were assayed for antimutagenicity against MNU in S. typhimurium TA1535. Finally, five components with antimutagenic activity against MNU were identified as Glyurallin A, glyasperin B, licoricidin, 1-methoxyphaseollin, and licoisoflavone B.
CONCLUSIONS:
The five components were demonstrated to possess an antigenotoxic effect against carcinogenic MNU for the first time. It is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.

Glyurallin A Description

Source:	The roots of Glycyrrhiza aspera.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Glyurallin A
Price:
CAS No.:	199331-36-7
Catalog No.:	CFN89255
Molecular Formula:	C₂₁H₂₀O₅
Molecular Weight:	352.38 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The roots of Glycyrrhiza aspera.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-mutagenic Compound Library Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.8378 mL	14.1892 mL	28.3785 mL	56.7569 mL	70.9461 mL
5 mM	0.5676 mL	2.8378 mL	5.6757 mL	11.3514 mL	14.1892 mL
10 mM	0.2838 mL	1.4189 mL	2.8378 mL	5.6757 mL	7.0946 mL
50 mM	0.0568 mL	0.2838 mL	0.5676 mL	1.1351 mL	1.4189 mL
100 mM	0.0284 mL	0.1419 mL	0.2838 mL	0.5676 mL	0.7095 mL

CFN96054	Phaseollidin hydrate	76122-57-1	342.4	C₂₀H₂₂O₅
CFN96024	Cristacarpin	74515-47-2	354.4	C₂₁H₂₂O₅
CFN96166	Orientanol A	190381-82-9	388.4	C₂₁H₂₄O₇
CFN98069	Barbacarpan	213912-46-0	322.4	C₂₀H₁₈O₄
CFN97946	Phaseollin	13401-40-6	322.4	C₂₀H₁₈O₄
CFN98647	Anhydrotuberosin	41347-49-3	320.3	C₂₀H₁₆O₄
CFN96878	1-Methoxyphaseollidin	65428-13-9	354.40	C₂₁H₂₂O₅
CFN95107	Tuberosin	41347-45-9	338.4	C₂₀H₁₈O₅
CFN97592	Hydroxytuberosone	95456-43-2	354.36	C₂₀H₁₈O₆
CFN89255	Glyurallin A	199331-36-7	352.38	C₂₁H₂₀O₅