Science | Nature | Cell | View More
Natural Products
Gynuramine
Gynuramine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Gynuramine
Price:
CAS No.: 85611-43-4
Catalog No.: CFN00373
Molecular Formula: C18H25NO6
Molecular Weight: 351.40 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Gynura japonica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Weizmann Institute of Science (Israel)
  • Technical University of Denmark (Denmark)
  • Colorado State University (USA)
  • Lodz University of Technology (Poland)
  • Srinakharinwirot University (Thailand)
  • Institute of Bioorganic Chemist... (Poland)
  • Universidade Federal de Pernamb... (Brazil)
  • Agricultural Research Organizat... (Israel)
  • Anna University (India)
  • Utrecht University (Netherlands)
  • Medical University of Gdansk (Poland)
  • More...
Package
Featured Products
Lobetyolin

Catalog No: CFN99104
CAS No: 136085-37-5
Price: $168/20mg
Shikonin

Catalog No: CFN99907
CAS No: 517-88-4
Price: $50/20mg
Berberine

Catalog No: CFN98049
CAS No: 2086-83-1
Price: $40/20mg
N-p-Coumaroyloctopamine

Catalog No: CFN97706
CAS No: 66648-45-1
Price: $218/10mg
Fraxidin

Catalog No: CFN98860
CAS No: 525-21-3
Price: $268/10mg
Gomisin A

Catalog No: CFN98990
CAS No: 58546-54-6
Price: $60/20mg
8-Prenylkaempferol

Catalog No: CFN92346
CAS No: 28610-31-3
Price: $ / mg
Erythrodiol

Catalog No: CFN98914
CAS No: 545-48-2
Price: $138/10mg
Senkyunolide A

Catalog No: CFN99594
CAS No: 62006-39-7
Price: $90/20mg
Liquiritigenin

Catalog No: CFN99156
CAS No: 578-86-9
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Gynuramine is a natural product from Gynura japonica.
In vitro:
Planta Med. 1998 Apr;64(3):259-63.
Generation and Characterization of Monoclonal Antibodies against the Pyrrolizidine Alkaloid Retrorsine[Pubmed: 9581524 ]
Monoclonal antibodies against retrorsine were established using a retrorsine-hemisuccinate::bovine-thyroglobuline conjugate as antigen for immunization.
METHODS AND RESULTS:
In competitive enzyme-linked immunoassays the specificity of the obtained antibodies was tested with 20 different pyrrolizidine alkaloids. Among these the alkaloids acetylGynuramine, Gynuramine, integerrimine, neoplatyphylline, platyphylline, rosmarinine, senecionine, and seneciphylline were able to bind the antibody. There was no cross-reactivity with the alkaloids senkirkine, angeloyl-heliotridine, heliotridine, axillarine, anacrotine, monocrotaline, madurensine, otosenine, retronecine, tussilagine, triangularine, and jacoline as well as with seneciphylline N-oxide.
CONCLUSIONS:
From this antigen spectrum it can be concluded that besides the necic structure itself the dominant and discriminative epitope consists of the exocyclic ethylidene group of the various diesters.
Gynuramine Description
Source: The herbs of Gynura japonica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
threo-Guaiacylglycerol-beta-conife...

Catalog No: CFN95417
CAS No: 650600-33-2
Price: $318/5mg
Ganoderenic acid K

Catalog No: CFN95469
CAS No: 942950-94-9
Price: $318/10mg
Schisphenlignan I

Catalog No: CFN95586
CAS No: 1542234-14-9
Price: $318/5mg
1-Methyl-2,8-dihydroxy-3-carboxy-9...

Catalog No: CFN95101
CAS No: 1401414-53-6
Price: $338/5mg
8-epi-Confertin

Catalog No: CFN95509
CAS No: 110115-60-1
Price: $318/5mg
Isosaponarin 2''-O-glucoside (Isov...

Catalog No: CFN95296
CAS No: 63316-27-8
Price: $318/10mg
Methyl ganoderate E

Catalog No: CFN95582
CAS No: 98718-43-5
Price: $413/5mg
Dioscoreside C

Catalog No: CFN95345
CAS No:
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8458 mL 14.2288 mL 28.4576 mL 56.9152 mL 71.144 mL
5 mM 0.5692 mL 2.8458 mL 5.6915 mL 11.383 mL 14.2288 mL
10 mM 0.2846 mL 1.4229 mL 2.8458 mL 5.6915 mL 7.1144 mL
50 mM 0.0569 mL 0.2846 mL 0.5692 mL 1.1383 mL 1.4229 mL
100 mM 0.0285 mL 0.1423 mL 0.2846 mL 0.5692 mL 0.7114 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Lobetyolin

Catalog No: CFN99104
CAS No: 136085-37-5
Price: $168/20mg
Shikonin

Catalog No: CFN99907
CAS No: 517-88-4
Price: $50/20mg
Berberine

Catalog No: CFN98049
CAS No: 2086-83-1
Price: $40/20mg
N-p-Coumaroyloctopamine

Catalog No: CFN97706
CAS No: 66648-45-1
Price: $218/10mg
Fraxidin

Catalog No: CFN98860
CAS No: 525-21-3
Price: $268/10mg
Gomisin A

Catalog No: CFN98990
CAS No: 58546-54-6
Price: $60/20mg
8-Prenylkaempferol

Catalog No: CFN92346
CAS No: 28610-31-3
Price: $ / mg
Erythrodiol

Catalog No: CFN98914
CAS No: 545-48-2
Price: $138/10mg
Senkyunolide A

Catalog No: CFN99594
CAS No: 62006-39-7
Price: $90/20mg
Liquiritigenin

Catalog No: CFN99156
CAS No: 578-86-9
Price: $30/20mg
Tags: buy Gynuramine | Gynuramine supplier | purchase Gynuramine | Gynuramine cost | Gynuramine manufacturer | order Gynuramine | Gynuramine distributor