|Description:||1. Inokosterone is an analgesic drug. |
2. Inokosterone shows high insect moulting hormone activity.
|Source:||The roots of Achyranthes bidentata Blume.|
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.0807 mL||10.4037 mL||20.8073 mL||41.6146 mL||52.0183 mL|
|5 mM||0.4161 mL||2.0807 mL||4.1615 mL||8.3229 mL||10.4037 mL|
|10 mM||0.2081 mL||1.0404 mL||2.0807 mL||4.1615 mL||5.2018 mL|
|50 mM||0.0416 mL||0.2081 mL||0.4161 mL||0.8323 mL||1.0404 mL|
|100 mM||0.0208 mL||0.104 mL||0.2081 mL||0.4161 mL||0.5202 mL|
Arch Biochem Biophys. 2011 Sep 1;513(1):27-35.
|C-26 vs. C-27 hydroxylation of insect steroid hormones: regioselectivity of a microsomal cytochrome P450 from a hormone-resistant cell line.[Pubmed: 21763268]|
|We studied the 25-desoxy analog of 20-hydroxyecdysone, ponasterone A, to elucidate the stereochemistry of the expected 26-hydroxy product, Inokosterone, which occurs as C-25 epimers in nature. We identified the predominant metabolite as the C-25 R epimer of Inokosterone on comparison by RP-HPLC with the (25R)- and (25S)-epimers the stereochemistry of which was confirmed by X-ray crystallography. (25R)-Inokosterone was further oxidized to the 26-aldehyde identified by mass spectroscopy, borohydride reduction and metabolic transformation to 26-carboxylic acid. The (25S)-epimers of Inokosterone and its aldehyde were minor products.|
Arch Pharm Res. 2012 Aug;35(8):1449-55.
|High performance liquid chromatography used for quality control of Achyranthis Radix.[Pubmed: 22941488]|
|To establish a standard of quality control and to identify reliable Achyranthis Radix, three phytoecdysones including ecdysterone (1), 25R-Inokosterone (2) and 25S-Inokosterone (3) were determined by quantitative HPLC/UV analysis. Three phytoecdysones were separated with an YMC J'sphere ODS C(18) column (250 mm × 4.6 mm, 4 μm) by isocratic elution using 0.1% formic acid in water and acetonitrile (85:15, v/v%) as the mobile phase. The flow rate was 1.0 mL/min and the UV detector wavelength was set at 245 nm.|