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    Isopropyl ferulate
    Isopropyl ferulate
    Information
    CAS No. 59831-94-6 Price
    Catalog No.CFN93263Purity>=98%
    Molecular Weight236.26Type of CompoundPhenylpropanoids
    FormulaC13H16O4Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison
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    Isopropyl ferulate Description
    Source: The herbs of Ligusticum chuanxiong Hort.
    Biological Activity or Inhibitors:
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    PMID: 29328914

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    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.2326 mL 21.1631 mL 42.3263 mL 84.6525 mL 105.8156 mL
    5 mM 0.8465 mL 4.2326 mL 8.4653 mL 16.9305 mL 21.1631 mL
    10 mM 0.4233 mL 2.1163 mL 4.2326 mL 8.4653 mL 10.5816 mL
    50 mM 0.0847 mL 0.4233 mL 0.8465 mL 1.6931 mL 2.1163 mL
    100 mM 0.0423 mL 0.2116 mL 0.4233 mL 0.8465 mL 1.0582 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Isopropyl ferulate References Information
    Citation [1]

    Enzyme Res. 2011;2011:718949.

    Synthesis of isopropyl ferulate using silica-immobilized lipase in an organic medium.[Pubmed: 21603272]
    Immobilization of lipases has proved to be a useful technique for improving an enzyme's activity in organic solvents. In the present study, the performance of a silica-immobilized lipase was evaluated for the synthesis of Isopropyl ferulate in DMSO. The biocatalyst was cross-linked onto the matrix with 1% glutaraldehyde. The effects of various parameters, molar ratio of ferulic acid to isopropyl alcohol (25 mM : 100 mM), concentration of biocatalyst (2.5-20 mg/mL), molecular sieves (25-250 mg/mL), and various salt ions, were studied consecutively as a function of percent esterification. Immobilized lipase at 25 mg/mL showed maximum esterification (~84%) of ferulic acid and isopropanol at a molar ratio of 25 mM : 100 mM, respectively, in DMSO at 45°C in 3 h under shaking (150 rpm). To overcome the inhibitory effect of water (a byproduct) if any, in the reaction mixture, molecular sieves (3 Å × 1.5 mm; 100 mg/mL) were added to the reaction mixture to promote the forward reaction. Salt ions like Ca(2+), Cd(2+), and Fe(2+) enhanced the activity of immobilized biocatalyst while a few ions like Co(2+), Zn(2+), Mg(2+), Mn(2+), Al(3+), and Na(+) had mild inhibitory effect. Approximately, one third of total decrease in the esterification efficacy was observed after the 5th repetitive cycle of esterification.