|Source:||The herb of Kadsura coccinea|
|Biological Activity or Inhibitors:||1. Kadsuracoccinic acid A has anticancer activity.
2. Kadsuracoccinic acid A induces significant cleavage arrest.
3. Kadsuracoccinic acid A may be related to the preservation of the progression of the M phase.
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.1336 mL||10.6678 mL||21.3356 mL||42.6712 mL||53.339 mL|
|5 mM||0.4267 mL||2.1336 mL||4.2671 mL||8.5342 mL||10.6678 mL|
|10 mM||0.2134 mL||1.0668 mL||2.1336 mL||4.2671 mL||5.3339 mL|
|50 mM||0.0427 mL||0.2134 mL||0.4267 mL||0.8534 mL||1.0668 mL|
|100 mM||0.0213 mL||0.1067 mL||0.2134 mL||0.4267 mL||0.5334 mL|
J Nat Prod. 2008 Apr;71(4):739-41.
|Kadsuracoccinic acids A-C, ring-A seco-lanostane triterpenes from Kadsura coccinea and their effects on embryonic cell division of Xenopus laevis.[Pubmed: 18271558]|
|Three new 3,4- seco-lanostanes, Kadsuracoccinic acid A - C ( 1- 3), were isolated from the medicinal plant Kadsura coccinea, in addition to the known compounds kadsuric acid ( 4) and micranoic acid A ( 5). The structures of 1- 3 were elucidated by analysis of their 2D-NMR spectroscopic data. Furthermore, the relative conformation of 1 was confirmed by an X-ray crystallographic study. This is the first report of a 3,4- seco-lanostane-type triterpene with a 17(20)-ene functional group. Treatment of cultured individual Xenopus laevis cells with 1 at the blastular stage arrested cleavage of these cells with an IC 50 of 0.32 microg/mL.|