Methylecgonine | CAS:7143-09-1 | Manufacturer ChemFaces

Methylecgonine

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Description:

Methylecgonine is a kind of anaesthetic.It in urine as an indicator of cocaine use.

In vitro:

Analyst. 2015 Sep 21;140(18):6254-9.

Rapid detection of cocaine, benzoylecgonine and methylecgonine in fingerprints using surface mass spectrometry.[Pubmed: 25977942]

Latent fingerprints provide a potential route to the secure, high throughput and non-invasive detection of drugs of abuse. In this study we show for the first time that the excreted metabolites of drugs of abuse can be detected in fingerprints using ambient mass spectrometry.
METHODS AND RESULTS:
Fingerprints and oral fluid were taken from patients attending a drug and alcohol treatment service. Gas chromatography mass spectrometry (GC-MS) was used to test the oral fluid of patients for the presence of cocaine and benzoylecgonine. The corresponding fingerprints were analysed using Desorption Electrospray Ionization (DESI) which operates under ambient conditions and Ion Mobility Tandem Mass Spectrometry Matrix Assisted Laser Desorption Ionization (MALDI-IMS-MS/MS) and Secondary Ion Mass Spectrometry (SIMS). The detection of cocaine, benzoylecgonine (BZE) and Methylecgonine (EME) in latent fingerprints using both DESI and MALDI showed good correlation with oral fluid testing. The sensitivity of SIMS was found to be insufficient for this application.
CONCLUSIONS:
These results provide exciting opportunities for the use of fingerprints as a new sampling medium for secure, non-invasive drug detection. The mass spectrometry techniques used here offer a high level of selectivity and consume only a small area of a single fingerprint, allowing repeat and high throughput analyses of a single sample.

Methylecgonine Description

Source:	The herbs of Erythroxylum coca
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Clin Chem. 1987 Jan;33(1):118-9.

Detection and confirmation of cocaine use by chromatographic analysis for methylecgonine in urine.[Pubmed: 3542285 ]

Methylecgonine is a common metabolite of cocaine in man.
METHODS AND RESULTS:
We prepared Methylecgonine and developed thin-layer chromatographic and gas-chromatographic methods for its detection in urine. Seventy urine specimens from our drug screening laboratory were tested by our method and by EMIT. Both methods were positive for 26 urines, and both were negative for 42 urines. The other two urines were shown to contain cocaine by GC/MS, and no detectable metabolites.
CONCLUSIONS:
We thus demonstrated that detection of Methylecgonine and cocaine is as sensitive a test for cocaine use as EMIT.

Product Name	Methylecgonine
Price:
CAS No.:	7143-09-1
Catalog No.:	CFN00190
Molecular Formula:	C₁₀H₁₇NO₃
Molecular Weight:	199.25 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Oil
Source:	The herbs of Erythroxylum coca
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Markers Compound Library Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	5.0188 mL	25.0941 mL	50.1882 mL	100.3764 mL	125.4705 mL
5 mM	1.0038 mL	5.0188 mL	10.0376 mL	20.0753 mL	25.0941 mL
10 mM	0.5019 mL	2.5094 mL	5.0188 mL	10.0376 mL	12.5471 mL
50 mM	0.1004 mL	0.5019 mL	1.0038 mL	2.0075 mL	2.5094 mL
100 mM	0.0502 mL	0.2509 mL	0.5019 mL	1.0038 mL	1.2547 mL

CFN00186	Convolvine	537-30-4	291.34	C₁₆H₂₁NO₄
CFN00187	Convolamine	500-56-1	305.37	C₁₇H₂₃NO₄
CFN00188	Darlingine	58471-10-6	219.28	C₁₃H₁₇NO₂
CFN00189	Ecgonine	481-37-8	185.22	C₉H₁₅NO₃
CFN00190	Methylecgonine	7143-09-1	199.25	C₁₀H₁₇NO₃
CFN00191	Benzoylecgonine	519-09-5	289.33	C₁₆H₁₉NO₄
CFN00192	Cinnamoylcocaine	521-67-5	329.4	C₁₉H₂₃NO₄
CFN00196	Knightinol	77053-06-6	289.37	C₁₇H₂₃NO₃
CFN00197	Acetylknightinol	77053-07-7	331.41	C₁₉H₂₅NO₄
CFN00198	6-beta-Hydroxyhyoscyamine	55869-99-3	305.37	C₁₇H₂₃NO₄