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    Nuezhenidic acid
    Nuezhenidic acid
    Information
    CAS No. 183238-67-7 Price
    Catalog No.CFN93220Purity>=98%
    Molecular Weight452.36Type of CompoundIridoids
    FormulaC17H24O14Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison
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    Nuezhenidic acid Description
    Source: The herbs of Ligustrum lucidum
    Biological Activity or Inhibitors:
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

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    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2106 mL 11.0531 mL 22.1063 mL 44.2126 mL 55.2657 mL
    5 mM 0.4421 mL 2.2106 mL 4.4213 mL 8.8425 mL 11.0531 mL
    10 mM 0.2211 mL 1.1053 mL 2.2106 mL 4.4213 mL 5.5266 mL
    50 mM 0.0442 mL 0.2211 mL 0.4421 mL 0.8843 mL 1.1053 mL
    100 mM 0.0221 mL 0.1105 mL 0.2211 mL 0.4421 mL 0.5527 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Nuezhenidic acid References Information
    Citation [1]

    Chinese Journal of Experimental Traditional Medical Formulae, 2014 , 20 (12) :14-17.

    Dynamic Changes of Neonuezhenide,Oleoside-11-methyl Ester and Nuezhenidic Acid in Wine Steaming Process of Ligustri Lucidi Fructus[Reference: WebLink]
    To analyze dynamic changes of three kinds of secoiridoid glycosides( neonuezhenide,oleoside-11-methyl ester and Nuezhenidic acid) in wine steaming process of Ligustri Lucidi Fructus. Method: Contents of neonuezhenide, oleoside-11-methyl ester and Nuezhenidic acid in crude and processed products of Ligustri Lucidi Fructus were determined by HPLC under processing time span in 4,8,12,16,20,24 h,mobile phase was acetonitrile( A)-0. 1% formic acid( B) with gradient elution( 0-19 min,12%-25% A),detection wavelength was set at 235 nm. Result: Linear range of neonuezhenide,oleoside-11-methyl ester,Nuezhenidic acid were 0. 034 5-3. 450,0. 005 86-0. 586,0. 028 6-2. 860 μg,average recoveries were 99. 49%,99. 02% and 97. 80%,respectively. After steamed with wine,contents of neonuezhenide and oleoside-11-methyl ester in Ligustri Lucidi Fructus decreased significantly,but the content of Nuezhenidic acid increased markedly; with extension of steaming time,contents of neonuezhenide and oleoside-11-methyl ester decreased gradually and the content of Nuezhenidic acid increased gradually up to a steady state in 24 h.Conclusion: After Ligustri Lucidi Fructus been steamed with wine,neonuezhenide and oleoside-11-methyl ester took qualitative changes while Nuezhenidic acid took quantitative changes,this study could provide experimental basis to explain processing mechanism and standardized management of Ligustri Lucidi Fructus.