|Biological Activity or Inhibitors:||1. Prerubialatin is a precursor of rubialatins A and B.
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.1908 mL||10.9541 mL||21.9082 mL||43.8164 mL||54.7705 mL|
|5 mM||0.4382 mL||2.1908 mL||4.3816 mL||8.7633 mL||10.9541 mL|
|10 mM||0.2191 mL||1.0954 mL||2.1908 mL||4.3816 mL||5.4771 mL|
|50 mM||0.0438 mL||0.2191 mL||0.4382 mL||0.8763 mL||1.0954 mL|
|100 mM||0.0219 mL||0.1095 mL||0.2191 mL||0.4382 mL||0.5477 mL|
Org Lett. 2015 Mar 20;17(6):1441-4.
|Biomimetic syntheses of rubialatins A, B and related congeners.[Pubmed: 25723050]|
|The first total syntheses of rubialatins A and B, two newly discovered naphthohydroquinone dimers, were achieved with high efficiency and elegancy through rationally designed biomimetic approaches. The tandem ring contraction/Michael addition/aldol reaction followed by oxidation enabled the rapid access of Prerubialatin from readily available precursors, which then diverted into rubialatins A and B via epoxidation and photoinduced skeletal rearrangement, respectively. Moreover, several new rubialatin congeners were also obtained along the synthetic tour, some of which were proved to be authentic natural products.|