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    Prerubialatin
    Information
    CAS No. 1667718-89-9 Price
    Catalog No.CFN96585Purity>=98%
    Molecular Weight456.45Type of CompoundQuinones
    FormulaC27H20O7Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Prerubialatin Description
    Source: The herbs of Rubia cordifolia
    Biological Activity or Inhibitors: 1. Prerubialatin is a precursor of rubialatins A and B.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1908 mL 10.9541 mL 21.9082 mL 43.8164 mL 54.7705 mL
    5 mM 0.4382 mL 2.1908 mL 4.3816 mL 8.7633 mL 10.9541 mL
    10 mM 0.2191 mL 1.0954 mL 2.1908 mL 4.3816 mL 5.4771 mL
    50 mM 0.0438 mL 0.2191 mL 0.4382 mL 0.8763 mL 1.0954 mL
    100 mM 0.0219 mL 0.1095 mL 0.2191 mL 0.4382 mL 0.5477 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Prerubialatin References Information
    Citation [1]

    Org Lett. 2015 Mar 20;17(6):1441-4.

    Biomimetic syntheses of rubialatins A, B and related congeners.[Pubmed: 25723050]
    The first total syntheses of rubialatins A and B, two newly discovered naphthohydroquinone dimers, were achieved with high efficiency and elegancy through rationally designed biomimetic approaches. The tandem ring contraction/Michael addition/aldol reaction followed by oxidation enabled the rapid access of Prerubialatin from readily available precursors, which then diverted into rubialatins A and B via epoxidation and photoinduced skeletal rearrangement, respectively. Moreover, several new rubialatin congeners were also obtained along the synthetic tour, some of which were proved to be authentic natural products.