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    Quassidine B
    Quassidine B
    Information
    CAS No. 1207862-37-0 Price
    Catalog No.CFN96716Purity>=98%
    Molecular Weight452.51Type of CompoundAlkaloids
    FormulaC27H24N4O3Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Quassidine B Description
    Source: The stems of Picrasma quassioides.
    Biological Activity or Inhibitors:
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2099 mL 11.0495 mL 22.099 mL 44.1979 mL 55.2474 mL
    5 mM 0.442 mL 2.2099 mL 4.4198 mL 8.8396 mL 11.0495 mL
    10 mM 0.221 mL 1.1049 mL 2.2099 mL 4.4198 mL 5.5247 mL
    50 mM 0.0442 mL 0.221 mL 0.442 mL 0.884 mL 1.1049 mL
    100 mM 0.0221 mL 0.1105 mL 0.221 mL 0.442 mL 0.5525 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Quassidine B References Information
    Citation [1]

    Journal of Natural Products, 2010, 73(2):167-171.

    Quassidines A-D, bis-beta-carboline alkaloids from the stems of Picrasma quassioides.[Pubmed: 20095629]
    Four new bis-beta-carboline alkaloids, quassidine A,Quassidine B, quassidine C, quassidine D (1-4), together with a known alkaloid, picrasidine C (5), were isolated from the stems of Picrasma quassioides. Quassidine A (1) is the first reported bis-beta-carboline alkaloid possessing a novel cyclobutane moiety. The structures of the new compounds were determined on the basis of their 1D and 2D NMR and X-ray diffraction data. A possible biogenetic pathway for these alkaloids was proposed, and all compounds were evaluated for anti-inflammatory activity. Only quassidine A (1) showed weak activity.