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    Rubrosterone
    Information
    CAS No. 19466-41-2 Price
    Catalog No.CFN90840Purity>=98%
    Molecular Weight334.4Type of CompoundSteroids
    FormulaC19H26O5Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: Rubrosterone is an insect-molting C19-steroid.
    In vivo:
    J Agric Food Chem. 2015 Jul 29;63(29):6596-602.
    Innovative Approach to the Accumulation of Rubrosterone by Fermentation of Asparagus filicinus with Fusarium oxysporum.[Pubmed: 2614546]

    METHODS AND RESULTS:
    Plasma lipid, lipoprotein lipid, and low-density lipoprotein (LDL) apolipoprotein B (Apo B) levels were measured in 34 patients who had undergone heart transplantation and in two patients who had undergone heart-lung transplantation. In contrast to initial reports, atherogenic dyslipoproteinemias were common, with 14% of patients having increased LDL cholesterol levels, 16.7% increased triglyceride levels, 8.3% decreased high-density lipoprotein (HDL) cholesterol levels, and 22.2% increased LDL Apo B levels. Of interest, 14% of patients had an HDL cholesterol level greater than the 95th percentile of the general population. In four patients coronary arteriosclerosis developed after transplantation. All had an atherogenic dyslipoproteinemia. One had type II hypercholesterolemia, and one had isolated low HDL cholesterol levels. Two had hyperapobetalipoproteinemia, one of whom also had low HDL cholesterol levels.
    CONCLUSIONS:
    The results establish that atherogenic dyslipoproteinemias are frequent in patients after heart transplantation and suggest that these dyslipoproteinemias, along with rejection, may play a role in the pathogenesis of arteriosclerosis after transplantation.
    Rubrosterone Description
    Source: The herbs of Achyranthes bidentata Blume
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9904 mL 14.9522 mL 29.9043 mL 59.8086 mL 74.7608 mL
    5 mM 0.5981 mL 2.9904 mL 5.9809 mL 11.9617 mL 14.9522 mL
    10 mM 0.299 mL 1.4952 mL 2.9904 mL 5.9809 mL 7.4761 mL
    50 mM 0.0598 mL 0.299 mL 0.5981 mL 1.1962 mL 1.4952 mL
    100 mM 0.0299 mL 0.1495 mL 0.299 mL 0.5981 mL 0.7476 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Asian Nat Prod Res. 2003 Dec;5(4):237-40.
    Phytoecdysteroid constituents from Cyanotis arachnoidea.[Pubmed: 14604231]
    Four phytoecdysteroids that have only 19 or 21 carbons, named 11alpha-hydroxyRubrosterone (1), dihydroxyRubrosterone (2), Rubrosterone (3) and poststerone (4), were isolated from the whole plant of Cyanotis arachnoidea C.B. Clarke. Among them, 1 was a new compound. Their structures were elucidated by spectroscopic methods.