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    Securitinine
    Securitinine
    Information
    CAS No. 13861-71-7 Price
    Catalog No.CFN96678Purity>=98%
    Molecular Weight247.29Type of CompoundAlkaloids
    FormulaC14H17NO3Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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  • Package
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    Securitinine Description
    Source: The leaves and twigs of Securinega suffruticosa.
    Biological Activity or Inhibitors:
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.0438 mL 20.2192 mL 40.4384 mL 80.8767 mL 101.0959 mL
    5 mM 0.8088 mL 4.0438 mL 8.0877 mL 16.1753 mL 20.2192 mL
    10 mM 0.4044 mL 2.0219 mL 4.0438 mL 8.0877 mL 10.1096 mL
    50 mM 0.0809 mL 0.4044 mL 0.8088 mL 1.6175 mL 2.0219 mL
    100 mM 0.0404 mL 0.2022 mL 0.4044 mL 0.8088 mL 1.011 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Securitinine References Information
    Citation [1]

    Chinese Journal of Natural Medicines, 2006, 4(4):260-263.

    Chemical constituents of Securinega suffruticosa.[Reference: WebLink]
    Aim: To investigate the chemical constituents of the leaves and twigs of Securinega suffruticosa (Pall.) Rehd. Method: Column chromatographic methods were used to separate the chemical constituents whose structures were elucidated by means of physicochemical properties and spectral analysis. Result: Eleven compounds were isolated and identified as (-)-15β-ethoxy-14,15-dihydroviroallosecurinine (1), securinine (2), 14,15-dihydrosecurinine (3), 4-epiphyllanthine (4), Securitinine (5), viroallosecurinine (6), securinol A (7), secu' amamine A (8), ent-phyllanthidine (9), (+)-aquilegiolide (10) and (+)-menisdaurilide (11), respectively. Conclusion: Compound 1 is a novel compound. Compounds 4, 8, 10 and 11 were isolated from Securinega suffruticosa for the first time.