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    Valeriotetrate C
    Valeriotetrate C
    CAS No. 904891-20-9 Price
    Catalog No.CFN96459Purity>=98%
    Molecular Weight742.85Type of CompoundIridoids
    FormulaC37H58O15Physical DescriptionOil
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Valeriotetrate C Description
    Source: The herbs of Valeriana jatamansi
    Biological Activity or Inhibitors:
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.3462 mL 6.7308 mL 13.4617 mL 26.9233 mL 33.6542 mL
    5 mM 0.2692 mL 1.3462 mL 2.6923 mL 5.3847 mL 6.7308 mL
    10 mM 0.1346 mL 0.6731 mL 1.3462 mL 2.6923 mL 3.3654 mL
    50 mM 0.0269 mL 0.1346 mL 0.2692 mL 0.5385 mL 0.6731 mL
    100 mM 0.0135 mL 0.0673 mL 0.1346 mL 0.2692 mL 0.3365 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Valeriotetrate C References Information
    Citation [1]

    J Nat Prod. 2010 Oct 22;73(10):1723-6.

    Revision of the Structures of 1,5-Dihydroxy-3,8-epoxyvalechlorine, Volvaltrate B, and Valeriotetrate C from Valeriana jatamansi and V. officinalis.[Pubmed: 20853876]
    The structures of 1,5-dihydroxy-3,8-epoxyvalechlorine (1a) and volvaltrate B (6a), two new chlorinated iridoids isolated from Valeriana jatamansi and V. officinalis, respectively, were originally assigned on the basis of spectroscopic methods. Reinvestigation using X-ray analysis and chemical transformation revealed that the original assignment of H-7 in 1a and OH-8 in 6a should be inverted and that the structures should be revised to 1 and 6, respectively. Correspondingly, the structure of Valeriotetrate C (7a) should be revised to 7. Volvaltrate B (6) showed cytotoxic activity against the lung adenocarcinoma (A549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8), and hepatoma (Bel7402) cell lines, with IC50 values of 8.5, 2.0, 3.2, and 6.1 μM, respectively.