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    Vasicinol
    Information
    CAS No. 5081-51-6 Price
    Catalog No.CFN99009Purity> 95%
    Molecular Weight204.2Type of CompoundAlkaloids
    FormulaC11H12N2O2Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Vasicinol Description
    Source: The leaves of Adhatoda vasica Nees
    Biological Activity or Inhibitors: 1. Vasicinol is a transient hypotensive agent, cardiac depressant.
    2. Vasicinol is histamine antagonist,shows mild anticholinesterase activity.
    3. Vasicinol shows a high sucrase inhibitory activity, and the IC50 values was 250 μM.vasicinol could be an useful treatment for metabolic disorders.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.8972 mL 24.4858 mL 48.9716 mL 97.9432 mL 122.429 mL
    5 mM 0.9794 mL 4.8972 mL 9.7943 mL 19.5886 mL 24.4858 mL
    10 mM 0.4897 mL 2.4486 mL 4.8972 mL 9.7943 mL 12.2429 mL
    50 mM 0.0979 mL 0.4897 mL 0.9794 mL 1.9589 mL 2.4486 mL
    100 mM 0.049 mL 0.2449 mL 0.4897 mL 0.9794 mL 1.2243 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Vasicinol References Information
    Citation [1]

    Tetrahedron: Asymmetry Volume 7, Issue 1, 1996, Pages 25–28

    Reversal of absolute stereochemistry of the pyrrolo[2,1-b]quinazoline alkaloids vasicine, vasicinone, vasicinol and vasicinolone[Reference: WebLink]
    The previously assigned 3R configuration of (−)-vasicinone has been reversed and this pyrrolo[2,1-b]quinazoline-9-one has been shown to have the 3S-configuration (3) on the basis of an X-ray diffraction study of (+)-vasicinone hydrobromide. Likewise, the 3R stereochemistry assigned earlier to (−)-vasicine (peganine) (1) on the basis of an X-ray analysis of its hydrochloride has also been reversed by reinvestigation of the X-ray diffraction analysis of the hydrobromide. The absolute stereochemistry of the alkaloids (+)-Vasicinol (2) and Vasicinolone (5) which have been inter-related, should also have the 3S-configuration. A study of the 1H nmr spectroscopy of (−)-vasicine by the use of Mosher's method using MTPA [α-methoxy-α-(trifluoromethyl)phenylacetic acid] esters indicated an exception to this model for establishing the absolute configuration.