ChemFaces is a professional high-purity natural products manufacturer.
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More articles cited ChemFaces products.
Sci Rep. Jan. 2018International Journal of Mol. Med.2015 Mar 6.University of Limpopo2016J Ethnopharmacol. 2017 Feb 2;Acta Physiologiae Plantarum.2014 10.
J Breast Cancer2015 Jun;18(2):112-118.Oncotarget. 2017 Dec 23;Acta Biochim Pol.2015 May 26Sci Rep. 2017 Apr 11;Pharm Biol. 2017 Dec;
Sci Rep. 2017 Aug 15;J Ethnopharmacol.23 February 2017Viruses. 2017 Oct 3;9(10). British Jou. Med. & Med. Research2014 Jan 1
Our products had been exported to the following research institutions and universities, And still growing.
Max-Planck-Insitut (Germany)Universidade de Franca (Brazil)National Cancer Institute (USA)CSIRO - Agriculture Flagship (Australia)
Universidad Miguel Hernández (Spain)Almansora University (Egypt)Semmelweis Unicersity (Hungary)Cancer Research Initatives Found... (Malaysia)
Universidade do Porto (Portugal)University of Minnesota (USA)Aveiro University (Portugal)
|| cis-Mulberroside A shows high analgesic and anti-inflammatory activities, it can protect mice against ethanol-induced hepatic damage.|
||TNF-α | NO | NOS|
|Environ. Toxicol. Pharmacol., 2008,26(3):325-30. |
|Protective function of cis-mulberroside A and oxyresveratrol from Ramulus mori against ethanol-induced hepatic damage.[Pubmed: 21791383 ]|
|The aim of the study was to investigate the protective effects of oxyresveratrol and cis-Mulberroside A isolated from Ramulus mori on the liver of mice intoxicated with ethanol. |
METHODS AND RESULTS:
Animals were pretreated with different doses (30 and 60mg/kg of body weight) of oxyresveratrol and cis-Mulberroside A prior to the ethanol (9g/kg of body weight) orally for 7 days. Ethanol treatment induced the decrease of reduced glutathione level and antioxidant enzymes activities, the elevation of the lipid peroxidation and cytochrome P450 2E1 activity accompanied with the increase of iron concentration and mitochondrial permeability transition. Pretreatment with oxyresveratrol and cis-Mulberroside A restored the changes in the above parameters up to the basal level. The protective effects of the two active compounds were further supported by attenuation of the degree of tissue damage and the regulation of the expression of TNF-α.
It could be concluded that oxyresveratrol and cis-Mulberroside A from R. mori could protect mice against ethanol-induced hepatic damage.
cis-Mulberroside A Description
||The root barks of Morus alba L.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Fitoterapia, 2009, 81(3):214-8. |
|Anti-inflammatory and analgesic properties of cis-mulberroside A from Ramulus mori.[Pubmed: 19755140 ]|
|This study examined the analgesic and anti-inflammatory actions of cis-Mulberroside A isolated from Ramulus mori in several models of inflammatory pain in mice. |
METHODS AND RESULTS:
cis-Mulberroside A (25 and 50mg/kg) given by p.o. route 30 min before challenge produced a dose-dependent inhibition of the acetic acid-induced pain and Evans blue leakage in mice. In addition, this compound exhibited significant systemic anti-inflammatory activity in carrageenan-induced mouse paw edema in a concentration-related manner (33.1-68.5% inhibition), and similar results were achieved in formalin test. Suppressive effects of cis-Mulberroside A on the production of NO and expression of inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-stimulated macrophages were also assessed. Collectively, cis-Mulberroside A showed high analgesic and anti-inflammatory activities.
The above results will be the supporting evidence for the potential anti-rheumatoid activity of R.mori in Chinese traditional medicine.