|Source:||The bark of Suregada multiflora.|
|Biological Activity or Inhibitors:||1. ent-16-Kaurene-3beta,15beta,18-triol, ent-16-kaurene-3beta,15beta-diol,abbeokutone,and helioscopinolide A possess appreciable anti-allergic activities in RBL-2H3 cells model with IC50 values ranging from 22.5 to 42.2 microM.
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||3.1201 mL||15.6006 mL||31.2012 mL||62.4025 mL||78.0031 mL|
|5 mM||0.624 mL||3.1201 mL||6.2402 mL||12.4805 mL||15.6006 mL|
|10 mM||0.312 mL||1.5601 mL||3.1201 mL||6.2402 mL||7.8003 mL|
|50 mM||0.0624 mL||0.312 mL||0.624 mL||1.248 mL||1.5601 mL|
|100 mM||0.0312 mL||0.156 mL||0.312 mL||0.624 mL||0.78 mL|
Phytochemistry. 2006 Dec;67(24):2630-4.
|Potential anti-allergic ent-kaurene diterpenes from the bark of Suregada multiflora.[Pubmed: 17095024 ]|
|Two ent-kaurene diterpenes, ent-16-Kaurene-3beta,15beta,18-triol (1) and ent-3-oxo-16-kaurene-15beta,18-diol (2), were isolated from a dichloromethane extract of the bark of Suregada multiflora along with five known diterpenes:ent-16-kaurene-3beta,15beta-diol (3), abbeokutone (4), helioscopinolide A (5), helioscopinolide C (6) and helioscopinolide I (7). Their structures were elucidated on the basis of spectroscopic analysis. Compounds 1-7 possessed appreciable anti-allergic activities in RBL-2H3 cells model with IC50 values ranging from 22.5 to 42.2 microM.|