ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Int J Mol Sci. 2017 May 11;Front Pharmacol. 2016 Nov 30Sci Rep. 2017 Apr 11;Preprints.25 Dec. 2017;Chemistr of plant2016021195
Semyung UniversityJan. 2017;Integr Med Res.2017 Dec;BMC Pharmacol Toxicol. 2018 Jan 31;University of Limpopo2016Front Immunol.2017 Nov 13;
Korean j.of Pharm.Dec.2017;Chem Biol Interact. 2016 Dec 25Am J Chin Med.2016;44(6)Tea Res. Ins. Of ChinaJuly 13, 2017;
Our products had been exported to the following research institutions and universities, And still growing.
Vin?a Institute of Nuclear Scien... (Serbia)University of East Anglia (United Kingdom)Technical University of Denmark (Denmark)Sapienza University of Rome (Italy)
Harvard University (USA)Universidad de Buenos Aires (Argentina)Instituto Politécnico de Bragan?a (Portugal)Aveiro University (Portugal)
Charles Sturt University (Denmark)University of Maryland School of... (USA)Korea Institute of Oriental Medi... (Korea)
||The bark of Suregada multiflora.
|Biological Activity or Inhibitors:
||1. ent-16-Kaurene-3beta,15beta,18-triol, ent-16-kaurene-3beta,15beta-diol,abbeokutone,and helioscopinolide A possess appreciable anti-allergic activities in RBL-2H3 cells model with IC50 values ranging from 22.5 to 42.2 microM.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
ent-16-Kaurene-3beta,15beta,18-triol References Information
Phytochemistry. 2006 Dec;67(24):2630-4.
|Potential anti-allergic ent-kaurene diterpenes from the bark of Suregada multiflora.[Pubmed: 17095024 ]|
|Two ent-kaurene diterpenes, ent-16-Kaurene-3beta,15beta,18-triol (1) and ent-3-oxo-16-kaurene-15beta,18-diol (2), were isolated from a dichloromethane extract of the bark of Suregada multiflora along with five known diterpenes:ent-16-kaurene-3beta,15beta-diol (3), abbeokutone (4), helioscopinolide A (5), helioscopinolide C (6) and helioscopinolide I (7). Their structures were elucidated on the basis of spectroscopic analysis. Compounds 1-7 possessed appreciable anti-allergic activities in RBL-2H3 cells model with IC50 values ranging from 22.5 to 42.2 microM.