1. 6,7-Dihydroxycoumarin has anticoagulant effect.
2. 6,7-Dihydroxycoumarin acts as a photosensitizer for DNA damage.
3. 6,7-Dihydroxycoumarin can quench the inner fluorescence of bovine serum albumin.
1. Ginsenoside Ro shows no hemolytic nor cytotoxic activities.
2. Ginsenoside Ro demonstrates significant anti-thrombic, anti-inflammatory, and anti-hepatitis activities in experimental models.
1. Bavachin is a weak antioxidant.
2. Bavachin acts as a weak phytoestrogen by binding and activating the estrogen receptor.
3. Bavachin stimulates bone formation and has potential activity against osteoporosis.
4. Bavachin has antimutagenic effect, shows inhibitory activities against the antigen-induced degranulation.
5. Bavachin has anti-inflammation effect, can protect cartilage from inflammation-mediated damage in joints of osteoarthritis patients, through decreasing IL-1 beta-induced activation of IKK-I kappaB alpha-NF-kappaB signaling pathway .
1. Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities.
2. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the generation of TNF-α and IL-6, the metabolism of drugs metabolized via CYP2C9 and CYP2E1.
3. Eleutheroside E may treat rheumatoid arthritis or increase the toxicity of the drugs.
1. Astragalin may be a potential agent in the treatment of osteoarthritis.
2. Astragalin can be effective in allaying ROS-promoted bronchial fibrosis through inhibiting autophagosome formation in airways.
3. Astragalin ameliorates oxidative stress-associated epithelial eosinophilia and apoptosis through disturbing TLR4-PKCβ2-NADPH oxidase-responsive signaling.
4. Astragalin exerts anti-inflammatory properties possibly via the inactivation of TLR4-mediated NF-κB and mitogen-activated protein kinases signaling pathways in LPS-stimulated mMECs.
5. Astragalin exerts anti-inflammatory properties in LPS-mediated mastitis, possibly through inhibiting inhibition of the NF-κB signaling pathway, which mediates the expression of pro-inflammatory cytokines.