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  • Bioactive Products
    Catalog No. Information
    CFN96041 Cepharadione A

    1. Cepharadione A, a naturally occurring DNA damaging agent.
    CFN90626 Beta,beta-Dimethylacrylalkannin

    1. Beta,beta-Dimethylacrylalkannin has radical scavenging activity.
    2. Beta,beta-Dimethylacrylalkannin can be potential therapeutics against tumor cell growth because of its unique DNA damaging abilities additional to enzyme inhibition similar to those of doxorubicin.
    3. Beta,beta-Dimethylacrylalkannin shows remarkable cytotoxic activity against HT-29, MDA-MB-231 and PC-3 cell lines, comparable or stronger than the other compounds and positive control CPT-11 (CAMPTOSTAR®, irinotecan) with IC50 values in between 0.1uM and 1uM; it has great potential as topo I inhibitors compared to other compounds and CPT-11, with 2-3uM inhibition value.
    4.Beta,beta-Dimethylacrylalkannin exhibits inhibitory activities on PTP1B with IC50 values of 0.36±0.08 umol·L-1, it may be a new type of leading compounds for the treatment of diabetes.