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  • Bioactive Products
    Catalog No. Information
    CFN90029 Histamine

    1. Histamine increases endothelial permeability and inhibits the ConA-induced ascites, presumably due to its known hypotonic effect.
    2. Histamine promotes the pathogenesis of experimental allergic asthma in mice via the Histamine H4 -receptor (H4 R).
    3. Histamine increases Nav1.8 expression in primary afferent neurons via H2 receptor-mediated pathway and thereby contributes to neuropathic pain, H2 receptor antagonists may potentially be used as analgesics for patients with neuropathic pain.
    CFN90321 Cinnamic aldehyde

    1. Cinnamic aldehyde exhibits excellent anti-inflammatory activities and antidepressant-like effects in stressed mid-aged rats as a COX-2 inhibitor.
    2. Cinnamic aldehyde induces apoptosis of CML cells in vitro, down-regulation of the expression and function of BCR-ABL may be one of its most important anti-leukemia mechanisms.
    3. Cinnamic aldehyde and cinnamic acid are cardioprotective in a rat model of ischemic myocardial injury, the mechanism is related to anti-oxidative and anti-inflammatory properties.
    CFN96027 Falcarinol

    1. Falcarinol has effects on CaCo-2 cells appear to be biphasic, inducing pro-proliferative and apoptotic characteristics at low and high concentrations of Falcarinol, respectively.
    2. Falcarinol-associated dermatitis is due to antagonism of the CB(1) receptor in keratinocytes, leading to increased chemokine expression and aggravation of histamine action.