|Source:||The herbs of Mangifera indica|
|Biological Activity or Inhibitors:||1. 1,5,6-Trihydroxy-3-methoxyxanthone exhibits scavenging activity at 10 uM, it can reduce the viability of HL-60 cells significantly with IC50 values of 28.9 uM.
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||3.6467 mL||18.2335 mL||36.4671 mL||72.9341 mL||91.1677 mL|
|5 mM||0.7293 mL||3.6467 mL||7.2934 mL||14.5868 mL||18.2335 mL|
|10 mM||0.3647 mL||1.8234 mL||3.6467 mL||7.2934 mL||9.1168 mL|
|50 mM||0.0729 mL||0.3647 mL||0.7293 mL||1.4587 mL||1.8234 mL|
|100 mM||0.0365 mL||0.1823 mL||0.3647 mL||0.7293 mL||0.9117 mL|
Food Science & Biotechnology, 2013, 22(4):945-949.
|Isolation of xanthones from adventitious roots of St. John’s Wort (Hypericum perforatum L.) and their antioxidant and cytotoxic activities.[Reference: WebLink]|
|In this phytochemical study, 5 xanthones, 1,3,5,6-tetrahydroxyxanthone , 1,5,6-Trihydroxy-3-methoxyxanthone , ferrxanthone , brasilixanthone B , and neolancerin  were isolated from adventitious roots of St. John’s wort (Hypericum perforatum L.). Compound 1–5 were evaluated for antioxidant activities using the intracellular reactive oxygen species (ROS) radical scavenging 2′,7′-dichlorfluorescein-diacetate (DCFDA) assay and for cytotoxic activity against the HL-60 human promyelocytic leukemia cells. Among them, compound 1–4 exhibited scavenging activity with inhibition values of 27.4–33.2% at 10 μM; compound 1, 2, and 4 reduced the viability of HL-60 cells significantly, with IC50 values of 31.5, 28.9, and 27.7 μM, respectively.|