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3-Oxo-24,25,26,27-tetranortirucall-7-en-23,21-olide
ChemFaces products have been cited in many studies from excellent and top scientific journals
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| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
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Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
3-Oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone shows significant inhibitory activities against human cancer cell lines in vitro. |
3-Oxo-24,25,26,27-tetranortirucall-7-en-23,21-olide Description
| Source: |
The herbs of Amoora dasyclada |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.5088 mL |
12.5439 mL |
25.0878 mL |
50.1756 mL |
62.7195 mL |
| 5 mM |
0.5018 mL |
2.5088 mL |
5.0176 mL |
10.0351 mL |
12.5439 mL |
| 10 mM |
0.2509 mL |
1.2544 mL |
2.5088 mL |
5.0176 mL |
6.272 mL |
| 50 mM |
0.0502 mL |
0.2509 mL |
0.5018 mL |
1.0035 mL |
1.2544 mL |
| 100 mM |
0.0251 mL |
0.1254 mL |
0.2509 mL |
0.5018 mL |
0.6272 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Chinese Traditional & Herbal Drugs, 2012, 43(1):38-42. | | Chemical constituents from Dysoxylum lenticellatum[Reference: WebLink] | To study the chemical constituents from the stems of Dysoxylum lenticellatum and their cytotoxic activities.
METHODS AND RESULTS:
Silica gel, RP-18, and Sephadex LH-20 column chromatography techniques were used for separation and purification of the compounds and extensive spectral analysis spectra were employed for structural elucidation. The cytotoxic activity was evaluated by MTT method. Twelve compounds were isolated from D. lenticellatum and their structures were identified as β-sitosterol (1), stigmasterol (2), 3-oxo-24, 25, 26, 27-tetranortirucall-7-en-23,21-lactone (3), 3α-hydroxy-24, 25, 26, 27-tetranortirucall-7-ene-23(21)-lactone (4), laxiracemosin H (5), laxiracemosin B (6), 24, 25-epoxy-tirucall-7-ene-3, 23-dione (7), butyrospermol (8), oleanolic acid (9), taraxerone (10), taraxerol (11), and 8-hydroxy-6-methoxy-3-pentylisocoumarin (12).
CONCLUSIONS:
All of these compounds are isolated from D. lenticellatum for the first time and the compounds 8, 10—12 are reported from the plants in Dysoxylum Bl. for the first time. What’s more, compounds 5 and 6 are tirucallane-type alkaloids and compound 3 shows significant inhibitory activities against human cancer cell lines in vitro. |
|
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