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Absouline
Absouline
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Absouline
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CAS No.: 112513-33-4
Catalog No.: CFN00240
Molecular Formula: C17H22N2O2
Molecular Weight: 286.37 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Hugonia oreogena
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Absouline is a natural product from Hugonia oreogena.
Absouline Description
Source: The herbs of Hugonia oreogena
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.492 mL 17.4599 mL 34.9199 mL 69.8397 mL 87.2996 mL
5 mM 0.6984 mL 3.492 mL 6.984 mL 13.9679 mL 17.4599 mL
10 mM 0.3492 mL 1.746 mL 3.492 mL 6.984 mL 8.73 mL
50 mM 0.0698 mL 0.3492 mL 0.6984 mL 1.3968 mL 1.746 mL
100 mM 0.0349 mL 0.1746 mL 0.3492 mL 0.6984 mL 0.873 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron, 2000 , 56 (13) :1837-1850
Synthèse des 1-amidopyrrolizidines naturelles, absouline et laburnamine, de dérivés et d'analogues pyrrolidinoimidazoliques[Reference: WebLink]
Natural 1-amidopyrrolizidines, Absouline and laburnamine, were synthesized via stable pyrrolizidin-1-one hydrobromide. Amides, ester derivatives and aminopyrrolidinoimidazole analogues were also prepared and their biological activities tested.
CFN00236Amabiline17958-43-9283.37C15H25NO4
CFN00237Cynaustine17958-39-3283.37C15H25NO4
CFN00238Supinine551-58-6283.37C15H25NO4
CFN00239Heleurine488-00-6297.39C16H27NO4
CFN00240Absouline112513-33-4286.37C17H22N2O2
CFN00241Isoabsouline112513-34-5286.37C17H22N2O2
CFN00242AnchustrigosineN/A471.59C24H41NO8
CFN00244Assamicadine126260-96-6309.36C16H23NO5
CFN00245Bohemamine72926-12-6262.30C14H18N2O3
CFN00246Callimorphine74991-73-4297.35C15H23NO5
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