ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
J Med Food. 2016 Dec;19(12)Biol Pharm Bull. 2018;41(1):65-72.Fitoterapia.2015 Jan;100:179-86.J Ethnopharmacol.2018 Jan 10;PLoS One. 2017 Mar 9;
Korean Society of Pharm. Sci.2017;Hum Exp Toxicol. 2016 Dec 9.Food Res Int. 2017 Jun;Journal of Pharmaceutical Analysis2016 Dec.Phytochemistry2017 Jun;
Sci Rep. 2016 Apr 27Evid Based Complement Alternat Med. 2016 May 24; Int J Mol Sci. 2018 Jan 23;Nat Prod Sci.2016 Jun;22(2)
Our products had been exported to the following research institutions and universities, And still growing.
St. Jude Children Research Hospi... (USA)Max Rubner-Institut (MRI) (Germany)Leibniz Institute of Plant Bioch... (Germany)Universite Libre de Bruxelles (Belgium)
University of Zurich (Switzerland)Seoul National University of Sci... (Korea)Julius Kühn-Institut (Germany)Yale University (USA)
Biotech R&D Institute (USA)University of Padjajaran (Indonesia)Uniwersytet Medyczny w ?odzi (Poland)
||Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin B can induce neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, and show moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.Broussonin B also can significantly inhibit adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay.
|Biol Pharm Bull. 2005 Sep;28(9):1798-800. |
|7-hydroxy-3-(4-hydroxybenzyl)chroman and broussonin b: neurotrophic compounds, isolated from Anemarrhena asphodeloides BUNGE, function as proteasome inhibitors.[Pubmed: 16141565 ]|
METHODS AND RESULTS:
The extract of Anemarrhenae Rhizoma (rhizomes of Anemarrhena asphodeloides BUNGE) showed neurotrophic activity toward rat pheochromocytoma (PC-12) cells. Bioassay-guided purification afforded four compounds, 2,6,4'-trihydroxy-4-methoxybenzophenone (1), 7-hydroxy-3-(4-hydroxybenzyl)chroman (2), Broussonin B (3), and cis-hinokiresinol (4).
Compounds 1-3 induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, while 4 was less active. In addition, compounds 2-4 showed moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.
Broussonin B Description
||The branches of Broussonetia papyrifera.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Bioorg Med Chem Lett. 2012 Apr 15;22(8):2760-3. |
|A new pancreatic lipase inhibitor from Broussonetia kanzinoki.[Pubmed: 22450131 ]|
METHODS AND RESULTS:
A new phenolic compound, broussonone A (1) were isolated from the stem barks of Broussonetia kanzinoki (Moraceae), together with two diphenylpropanes, broussonin A (2), Broussonin B (3), two flavans, 7,4'-dihydroxyflavan (4), 3',7-dihydroxy-4'-methoxyflavan (5), and two flavones, 3,7-dihydroxy-4'-methoxyflavone (6), 3,7,3'-trihydroxy-4'-methoxyflavone (7).
Compound 1 showed noncompetitive inhibitory activity on pancreatic lipase with an IC(50) of 28.4 μM. In addition, compounds 1-5 significantly inhibited adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay.
|Chemistry Letters,1980,3(3):339-340. |
|Broussonins A and B, new phytoalexins from diseased paper mulberry.[Reference: WebLink]|
METHODS AND RESULTS:
Isolation and structure elucidation of two phytoalexins (1 and 2), produced by diseased paper mulberry and designated as Broussonin A and Broussonin B, are described.
These phytoalexins are characterized structurally by a 1,3-diphenylpropane skeleton.