|Source:||The herbs of Salvia prionitis|
|Biological Activity or Inhibitors:|
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||3.1606 mL||15.8028 mL||31.6056 mL||63.2111 mL||79.0139 mL|
|5 mM||0.6321 mL||3.1606 mL||6.3211 mL||12.6422 mL||15.8028 mL|
|10 mM||0.3161 mL||1.5803 mL||3.1606 mL||6.3211 mL||7.9014 mL|
|50 mM||0.0632 mL||0.3161 mL||0.6321 mL||1.2642 mL||1.5803 mL|
|100 mM||0.0316 mL||0.158 mL||0.3161 mL||0.6321 mL||0.7901 mL|
Phytother Res. 2014 Jan;28(1):76-81.
|In vitro antimicrobial activity of royleanone derivatives against Gram-positive bacterial pathogens.[Pubmed: 23494919]|
|Infections caused by multiresistant bacterial pathogens are a significant problem worldwide, turning the search for natural compounds to act as alternatives to antibiotics of major importance. The aim of the present study was to investigate the in vitro antimicrobial activity of 7α-acetoxy-6β-hydroxyRoyleanone (1), isolated from Plectranthus grandidentatus (Lamiaceae), and 11 additional Royleanone abietane derivatives of 1 (2-12) against important Gram-positive human bacterial pathogens. Results showed that the aromatic and alkylic esters 2, 3 and 5 are more active than 1 against Enterococcus and Staphylococcus (minimum inhibitory concentration (MIC) values ranging from 0.98 to 62.50 µg/mL). Moreover, 7α-acetoxy-6β-hydroxy-12-O-(4-chloro)benzoylRoyleanone (2) gave rise to a new antibacterial-prototype (MIC values of 3.91-15.63 µg/mL against Staphylococcus and of 0.98-3.91 µg/mL against Enterococcus). The results showed that the compounds under analysis also present antimicrobial activity against resistant bacteria. The hydrophobic extra-interactions with bacterial targets seem to play an important role on the activity of Royleanones derivatives.|