ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
More articles cited ChemFaces products.
Inflammation.2015 Feb;38(1):445-55. Microchemical JournalMarch 2018;Am J Chin Med.2015 Jul 30:1-22.Tumour Biol.2015 Apr 12.Mol Med Rep.2015 Sep 21
Food Research InternationalJan. 2016Chem Biol Interact. 2016 Dec 25J Exp Bot. 2016 May 18.Tissue and Organ Culture (PCTOC)2016 Jun 28;Research on Crops.2017, Issue : 3
Int J Biol Macromol. 2018 Feb 12. J Ethnopharmacol.2016 Jun 25. Korean Society of Pharm. Sci.2017;Evidence-Based Comp. & Alter. Med.Dec. 27, 2015
Our products had been exported to the following research institutions and universities, And still growing.
Centralised Purchases Unit (CPU)... (India)Instytut Nawozów Sztucznych w P... (Poland)Seoul National University (Korea)Weizmann Institute of Science (Israel)
John Innes Centre (United Kingdom)Cancer Research Initatives Found... (Malaysia)Biotech R&D Institute (USA)Julius Kühn-Institut (Germany)
University of Maryland School of... (USA)Almansora University (Egypt)Shanghai University of TCM (China)
|| Vitexdoin A is a natural product from Vitex negundo.|
|J Nat Prod. 2009 Sep;72(9):1627-30. |
|Nitric oxide scavenging lignans from Vitex negundo seeds.[Pubmed: 19715321 ]|
METHODS AND RESULTS:
A new phenyldihydronaphthalene-type lignan, Vitexdoin A (1), a new phenylnaphthalene-type lignan alkaloid, vitedoamine B (2), four new phenylnaphthalene-type lignans, vitexdoins B-E (3-6), and four known lignan derivatives (7-10) were isolated from Vitex negundo seeds. Their structures were elucidated by detailed analyses of NMR, IR, and MS data. The ability of the isolates to prevent nitric oxide (NO) production by LPS-stimulated RAW 264.7 macrophages in a concentration-dependent manner was also studied.
Compounds 5, 6, and 9 were among the most potent NO production inhibitors, with IC(50) values of 0.13, 0.15, and 0.11 microM, respectively. The introduction of free hydroxy groups plays a vital role in the potency of these compounds.
Vitexdoin A Description
||The herbs of Vitex negundo
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.