ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Mol Med Rep.2014, 9(5):1653-9Molecules.2015, 20(10):19172-88Phytomedicine.2015, 22(11):1027-36Arch Pharm Res.2015, 38(6):1080-9J Basic Clin Physiol Pharmacol....2016...Mol Immunol. 2016, 78:121-132Mol Pharm.2017, 14(9):3164-3177Int J Mol Sci.2017, 18(5)
Molecules.2017, 22(11)J Cell Mol Med.2018, 22(9):4236-4242Nat Prod Sci.2018, 24(2):109-114Front Cell Infect Microbiol.2018, 8:292Front Aging Neurosci.2019, 11:230J Chromatogr B Analyt Technol Bio...2019...Plant Physiol Biochem.2019, 144:355-364Asian J Beauty Cosmetol...2019...
Asian Pac J Cancer Prev....2019...Int J Mol Sci.2019, 20(3):E651Chemistry of Plant Materials....2019...Molecules.2019, 24(21):E3834Journal of Functional Foods...2019...Chem Pharm Bull (Tokyo)....2019...Neurochem Int.2020, 133:104629
Our products had been exported to the following research institutions and universities, And still growing.
Leibniz Institute of Plant Bioc... (Germany)Tohoku University (Japan)University of Hertfordshire (United Kingdom)University of Padjajaran (Indonesia)
Charles University in Prague (Czech Republic)Sri Sai Aditya Institute of Pha... (India)Universiti Sains Malaysia (Malaysia)Medical University of Gdansk (Poland)
Deutsches Krebsforschungszentrum (Germany)Universita' Degli Studi Di Cagl... (Italy)Chulalongkorn University (Thailand)
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Lignans Compound Library
|| Vitexdoin A is a natural product from Vitex negundo.|
|J Nat Prod. 2009 Sep;72(9):1627-30. |
|Nitric oxide scavenging lignans from Vitex negundo seeds.[Pubmed: 19715321 ]|
METHODS AND RESULTS:
A new phenyldihydronaphthalene-type lignan, Vitexdoin A (1), a new phenylnaphthalene-type lignan alkaloid, vitedoamine B (2), four new phenylnaphthalene-type lignans, vitexdoins B-E (3-6), and four known lignan derivatives (7-10) were isolated from Vitex negundo seeds. Their structures were elucidated by detailed analyses of NMR, IR, and MS data. The ability of the isolates to prevent nitric oxide (NO) production by LPS-stimulated RAW 264.7 macrophages in a concentration-dependent manner was also studied.
Compounds 5, 6, and 9 were among the most potent NO production inhibitors, with IC(50) values of 0.13, 0.15, and 0.11 microM, respectively. The introduction of free hydroxy groups plays a vital role in the potency of these compounds.
Vitexdoin A Description
||The herbs of Vitex negundo
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.