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    4,2'-Dihydroxy-4'-methoxychalcone
    4,2'-Dihydroxy-4'-methoxychalcone
    Information
    CAS No. 63529-06-6 Price
    Catalog No.CFN89427Purity>=98%
    Molecular Weight270.28Type of CompoundChalcones
    FormulaC16H14O4Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    4,2'-Dihydroxy-4'-methoxychalcone Description
    Source: The resins of Xanthorrhoea hastilis R. BR.
    Biological Activity or Inhibitors: 1. 4,2'-Dihydroxy-4'-methoxychalcone shows allergy-preventive effects.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.6999 mL 18.4993 mL 36.9987 mL 73.9973 mL 92.4967 mL
    5 mM 0.74 mL 3.6999 mL 7.3997 mL 14.7995 mL 18.4993 mL
    10 mM 0.37 mL 1.8499 mL 3.6999 mL 7.3997 mL 9.2497 mL
    50 mM 0.074 mL 0.37 mL 0.74 mL 1.4799 mL 1.8499 mL
    100 mM 0.037 mL 0.185 mL 0.37 mL 0.74 mL 0.925 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    4,2'-Dihydroxy-4'-methoxychalcone References Information
    Citation [1]

    Chem Pharm Bull (Tokyo). 2007 Apr;55(4):675-8.

    Allergy-preventive flavonoids from Xanthorrhoea hastilis.[Pubmed: 17409571]
    Allergy-preventive activity was demonstrated for an extract of resins from Xanthorrhoea hastilis R. BR. in a search for allergy-preventive substances from natural sources. By bioassay-directed fractionation of this plant extract, a new flavanone, 3',5'-dihydroxy-7,4'-dimethoxyflavanone (1), and two new chalcones, 3,5,2'-trihydroxy-4,4'-dimethoxychalcone (2) and 5,2'-dihydroxy-3,4,4'-trimethoxychalcone (3), were isolated together with five known compounds, 5'-hydroxy-7,3',4'-trimethoxyflavanone (4), 3'-hydroxy-7,4'-dimethoxyflavanone (5), liquiritigenin 7-methyl ether (6), 4,2'-Dihydroxy-4'-methoxychalcone (7) and sakuranetin (8). The structures of 1, 2 and 3 were elucidated by spectroscopic methods. All of these compounds showed allergy-preventive effects.