(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one | CAS:120693-49-4

(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one

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Product Name	(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one
Price:
CAS No.:	120693-49-4
Catalog No.:	CFN96758
Molecular Formula:	C₂₁H₂₉NO
Molecular Weight:	311.46 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The fruits of Evodia rutaecarpa (Juss.) Benth.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one shows strong inhibitory activity on leukotriene biosynthesis in human polymorphonuclear granulocytes, and it is very effective against mycobacteria.

Targets:

Antifection

In vitro:

Planta Medica, 2009, 75(4):401-402.

Evaluation of the Anti-inflammatory Potential of Chinese Botanicals[Reference: WebLink]

Traditional Chinese medicine (TCM) has been using about 1300 plants for anti-inflammatory purposes.
METHODS AND RESULTS:
Activity guided isolation in a medium throughput approach has resulted in the discovery of a number of new drug leads. From the fruits of Evodia rutaecarpa (Juss.) Benth. (Rutaceae), several quinolinone alkaloids, like 1-methyl-2-nonyl-4(1H)-quinolinone, 1-methyl-2-(6Z)-6-undecenyl-4(1H)-quinolinone((Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one ), 1-methyl-2-(4Z,7Z)-4,7-tridecadienyl-4(1H)-quinolinone, evo-carpine and 1-methyl-2-(6Z,9Z)-6,9-pentadecadienyl-4(1H)-quinolinone, have been isolated which showed strong inhibitory activity on leukotriene biosynthesis in human polymorphonuclear granulocytes [1].
CONCLUSIONS:
They showed no cytotoxic activity and might bind to the lipid binding site of 5-LOX [2]. Moreover they were very effective against mycobacteria [3].

(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one Description

Source:	The fruits of Evodia rutaecarpa (Juss.) Benth.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-inflammatory Compound Library Inhibitors Compound Library Antibacterial Compound Library Alkaloids Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.2107 mL	16.0534 mL	32.1069 mL	64.2137 mL	80.2671 mL
5 mM	0.6421 mL	3.2107 mL	6.4214 mL	12.8427 mL	16.0534 mL
10 mM	0.3211 mL	1.6053 mL	3.2107 mL	6.4214 mL	8.0267 mL
50 mM	0.0642 mL	0.3211 mL	0.6421 mL	1.2843 mL	1.6053 mL
100 mM	0.0321 mL	0.1605 mL	0.3211 mL	0.6421 mL	0.8027 mL

CFN96290	1-Methyl-2-nonylquinolin-4(1H)-one	68353-24-2	285.4	C₁₉H₂₇NO
CFN96296	1-Methyl-2-undecylquinolin-4(1H)-one	59443-02-6	313.5	C₂₁H₃₁NO
CFN96758	(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one	120693-49-4	311.46	C₂₁H₂₉NO
CFN96759	Evocarpine	15266-38-3	339.52	C₂₃H₃₃NO
CFN92786	Dihydroevocarpine	15266-35-0	341.5	C₂₃H₃₅NO
CFN91687	1-Methyl-2-[(6Z,9Z)-6,9-pentadecadiene]-4(1H)-quinolone	120693-52-9	365.6	C₂₅H₃₅NO
CFN90072	Kynurenic acid	492-27-3	189.17	C₁₀H₇NO₃
CFN97215	1,4-Dihydro-1,2-dimethyl-4-oxo-3-quinolinecarboxylic acid	73281-83-1	217.2	C₁₂H₁₁NO₃
CFN96756	Ifflaiamine	31520-95-3	243.30	C₁₅H₁₇NO₂
CFN97248	Mallorepine	767-98-6	134.1	C₇H₆N₂O