Bioactive Products
| A unique collection of 518 natural compounds with Antioxidants biological activity for high throughput screening (HTS) and high content screening (HCS) | ||
| Catalog No: | B11 | Antioxidants Compound Library Screening Details |
| Size: | 1mg/well * 518 Compounds 2mg/well * 518 Compounds | |
| Cat. No. | Information |
| CFN97236 | Usnic acid Usnic acid has antitumoral, acaricidal, larvicidal, antiviral, antibiotic, antipyretic, analgesic,gastroprotective, antioxidative and anti-inflammatory activities. Use of reconstituted bovine type-I collagen-based films containing usnic acid can improve burn healing process in rats. Usnic acid perturbs various interrelated signaling pathways and that autophagy induction is a defensive mechanism against usnic acid-induced cytotoxicity; it disturbs calcium homeostasis, induces ER stress, and that Usnic acid-induced cellular damage occurs at least partially via activation of the Ca(2+) channel of SOCE. |
| CFN97239 | Artocarpin Artocarpin has anti- bactericidal effect, can reduce the viability of pneumococci by a factor of >1000, without obvious harm to lung epithelial cells. Artocarpin can prevent skin damage from UVB irradiation-induced photodamage in hairless mice and this is likely mediated through its antioxidant and anti-inflammation mechanisms.Artocarpin possesses potent 5alpha reductase inhibitory effect, it induces apoptosis in HSC-1 and T47D cells through modulation of MAPK and Akt/mTOR pathways, an extrinsic pathway, respectively. Artocarpin has an efficient lightening effect on UV-stimulated hyperpigmented dorsal skins of brownish guinea pigs. |
| CFN97252 | Cleomiscosin A Cleomiscosin A has antioxidant activity, it could be beneficial in preventing LDL oxidation in atherosclerotic lesions, it shows inhibitory activity to TNF-α secretion of the mouse peritoneal macrophages. Cleomiscosin A and brusatol are antitumor agents, have antileukemic principles. Cleomiscosin A methyl ether derivatives have anti-inflammatory activity. The mixture of three compounds (cleomiscosin A, B and C) is showing the significant protective effects against CCl(4)-induced hepatotoxicity in small animals and also coumarinolignoids are well tolerated by small animals in acute oral study. |
| CFN97259 | Ursolic acid Ursolic acid is a potential PPARγagonist, which has anti-tumor, chemopreventive, hepatoprotective, anti-inflammatory, antioxidant, antidepressant-like, antimicrobial activities, and anti-asthmatic effects. Ursolic acid also has antihyperlipidemic, hypoglycemic and direct cardiac effect, its antihypertensive effect is attributed to its potent diuretic-natriuretic-saluretic activity. Ursolic acid regulates NF-κB, VEGF, COX-2, Nrf2, ARE, IL-5, IL-13, IL-17and MAPK signaling pathways. |
| CFN97268 | N-trans-Feruloyl-3-methoxytyramine N-trans-Feruloyl-3-methoxytyramine shows significantly DPPH radical scavenging activities. |
