Natural Products
Cimifugin
| Catalog No. | CFN98612 |  |
| CAS No. | 37921-38-3 | |
| Molecular Weight: | 306.3 | |
| Molecular Formula | C16H18O6 | |
| DBs | [PubChem]:274951891 [ChEMBL]:3701 [PCIDB]:2421 |
Standard InChI:
InChI=1S/C16H18O6/c1-16(2,19)13-5-9-11(22-13)6-12-14(15(9)20-3)10(18)4-8(7-17)21-12/h4,6,13,17,19H,5,7H2,1-3H3/t13-/m0/s1
Biological Activity
Cimifugin, isolated from Peucedanum schottii, displays low to moderate inhibition towards AChE and BChE (3.12 and 21.63%, respectively) at 200 µg mL-1.[1]
Cimifugin evidently inhibits FITC-induced type 2 allergic contact dermatitis,and its mechanism might related to regulating the balance of Th1 /Th2 by inhibiting type 2 cytokines.[2]
Product
References
[1] Koziol E, Senol F S, Orhan I E, et al. Natl Prod Communicat, 2016, 6.
[2] Jiang X, Wang H, Gui L, et al. Pharmacol Clin Chinese Mat Med, 2014, 30(2):28-30.
[3] Wang X, Wang Z, Sun H, et al. Arzneimittel-Forschung, 2008, 58(9):445-50.
Product Use Citation
