Natural Products
Huperzia serrata (Thunb.) Trev.
Huperzia serrata (TCM = Qian Ceng Ta/Jin Bu Huan) is a plant known as a firmoss which contains the acetylcholinesterase inhibitor huperzine A. It is widely distributed over-the-counter as a nootropic and dietary supplement. It may also be used to treat Alzheimer's disease.This species is native to India and southeast Asia.
A new Lycopodium alkaloid, huperserratinine, was isolated from Huperziaserrata and its structure and NMR data were assigned unambiguously by a combination of NMR experiments and computer modelling calculations. The pH-zone refining centrifugal partition chromatography technique was used to separate the two acetylcholinesterase inhibitors huperzines A and B from a crude alkaloid extract of the club moss Huperziaserrata. Huperzine P (1), a new irregular fawcettimine-type Lycopodium alkaloid, was isolated from Huperziaserrata and the absolute stereostructure was established by 2D NMR and X-ray crystallographic analysis.
Research products of Huperzia serrata (Thunb.) Trev.
Catalog | Product Name | CAS Number | Manual |
---|---|---|---|
CFN99959 | Huperzine A | 120786-18-7 | |
CFN99960 | Huperzine B | 103548-82-9 | |
CFN99495 | 21-Episerratenediol | 1449-06-5 | |
CFN98216 | Serratenediol | 2239-24-9 | |
CFN98339 | Serratenediol diacetate | 27832-84-4 | |
CFN99958 | (-)-Huperzine A | 102518-79-6 | |
CFN99916 | Beta-Sitosterol | 83-46-5 | |
CFN98913 | Lupeol | 545-47-1 | |
CFN98848 | Physcion | 521-61-9 | |
CFN98843 | Apigenin | 520-36-5 |
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