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Natural Products
Catalog No. Information
CFN98595 Methylophiopogonanone A

Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties, it also has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulating the expression of MMP-9 and tight junction proteins.
CFN98596 Methylophiopogonanone B

Methylophiopogonanone B has inhibition of hypoxia-inducible factor (HIF)-1 alpha activity.Methylophiopogonanone B can inhibit melanosome transfer to keratinocytes as well as melanocyte dendrite outgrowth, it also suppress pigmentation in a three-dimensional skin culture model through the inhibition of melanocyte dendrite outgrowth, it could result in the creation of very unique cosmetic products that would precisely control the darkening or lightening of skin tone.
CFN90708 Methylophiopogonone A

Methylophiopogonone A is a natural product from Ophiopogon japonicus.
CFN80321 Methylophiopogonone B

Methylophiopogonone B is a natural product from Ophiopogon japonicus.
CFN92450 Methylsynephrine Hydrochloride

Reference standards.
CFN92148 Methyltanshinonate

Methyltanshinonate shows antiplasmodial and antitrypanosomal activities. It may have antioxidative activity.
CFN90160 Methysticin

Methysticin is a potent NF-kappaB inhibitor in kava with minimum toxicity, it possesses hepatotoxic, anticonvulsant and neuroprotective properties, it contributes to CYP1A1 induction.
CFN90426 Mevastatin

Mevastatin inhibits HMGCR (HMG-CoA reductase) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Mevastatin inhibits the differentiation of TAO derived orbital preadipocytes by blocking PPAR-gamma mRNA expression. Mevastatin induces cell growth inhibition and apoptosis in SACC cells, it triggers the phosphorylation of the EGFR and inhibits the c-Jun N-terminal kinase pathway.
CFN91035 Micheliolide

Micheliolide has antineoplastic, anti-inflammatory and immunomodulatory effects, it inhibits various inflammatory response and may serve as a neuroprotective agent in neuroinflammation-related neurodegenerative disorders. Micheliolide has potential as a candidate drug for the treatment of diabetic nephropathy, it can effectively attenuate the high glucose-stimulated activation of NF-κB, the degradation of IκBα, and the expression of MCP-1, TGF-β1 and FN in rat mesangial cells (MCs). Micheliolide also ameliorates liver steatosis by upregulating PPAR-γ expression, thereby inhibiting NF-κB-mediated inflammation and activating AMPK/mTOR-dependent autophagy.
CFN97124 Micranoic acid A

Reference standards.