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Natural Products
Catalog No. Information
CFN90589 Myristicin

Myristicin has anti-cholinergic, antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with its inhibition of NO, cytokines,chemokines, and growth factors in dsRNA-stimulated macrophages via the calcium pathway. Myristicin may antagonize the anxiolytic effects of midazolam, increase anxiety, and affect motor movements. Myristicin can induce apoptosis as characterised by alterations in the mitochondrial membrane potential, cytochrome c release, caspase-3 activation, PARP-cleavage and DNA fragmentation.
CFN91042 Myrrhone

Reference standards.
CFN90847 N-(3-Methoxybenzyl)oleamide

Macamides (N-(3-methoxybenzyl)oleamide (MAC 18:1), N-(3-methoxybenzyl)linoleamide (MAC 18:2) and N-(3-methoxybenzyl)linolenamide (MAC 18:3) )achieve their neuroprotective effects by binding to CB1 receptors to protect against Mn-induced toxicity in U-87 MG glioblastoma cells. Additionally these macamides, in a manner similar to the analogous endocannabinoid AEA, interact with other targets such as PPARγ to regulate metabolism and energy homeostasis, cell differentiation and inflammation.
CFN90846 N-(3-Methoxybenzyl)palmitamide

N-(3-methoxybenzyl)palmitamide is a promising inhibitor of fatty acid amide hydrolase (FAAH) and could potentially offer a good alternative for the treatment of pain, inflammation and CNS degenerative disorders. N-(3-Methoxybenzyl)palmitamide can counteract the toxicity produced by Aβ (25-35).
CFN91127 N-(p-Coumaroyl) serotonin

N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving vascular distensibility and in reducing cardiovascular risk.N-(p-Coumaroyl) serotonin has a suppressive effect on proinflammatory cytokine production from monocytes, and this effect is based in part on the suppression of cytokine mRNA expression through inhibition of NF-kappaB activation.
CFN99248 N1,N10-Bis(p-coumaroyl)spermidine

Reference standards.
CFN95256 N1,N5,N10-(E)-tri-p-coumaroylspermidine

N1,N5,N10-(E)-tri-p-coumaroylspermidine shows free radical-scavenging activity.
CFN95253 N1,N5,N10-(Z)-tri-p-coumaroylspermidine

N1,N5,N10-(Z)-tri-p-coumaroylspermidine shows weak inhibition effect on [3H]-5-HT reuptake in rat brain synaptosomes.
CFN90045 N-Acetylneuraminic acid

N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells.Synthesis of pyrrolidine analogues of N‐acetylneuraminic acid could as potential sialidase inhibitors. N-Acetylneuraminic acid-containing substances has growth-promoting effects on bifidobacteria, a number of N-acetylneuraminic acid-based compounds as potential rotavirus inhibitors.
CFN00293 N-Acetylnorloline

High levels of N-acetyl norloline and peramine may be of particular importance for developing 'friendly' endophyte-enhanced turf and pasture grasses that resist challenging lepidopteran pests. N-acetyl norloline, which is produced by the Max P endophyte, may be responsible for a new form of toxicity called equine fescue oedema in horses.