|A unique collection of 73 Antihyperglycemic natural compounds for high throughput screening (HTS) and high content screening (HCS).|
|Catalog No:||B545|| Antihyperglycemic Compound Library
|Size:||1mg/well * 73 Compounds|
2mg/well * 73 Compounds
1. D-pinitol exerts anti-inflammatory activity.
2. D-Pinitol exerts insulin-like activity, used for many diabetic associated conditions.
3. D-Pinitol is a safe nutrient to reduce calorie consumption when supplementing with creatine.
1. Chlorogenic acid exhibits remarkable antioxidative activity.
2. Chlorogenic acid has a wide range of antibacterial action.
3. Chlorogenic acid is an important intermediate in lignin biosynthesis.
4. Chlorogenic acid inhibits the inflammatory reaction in HSE via the suppression of TLR2/TLR9-Myd88 signaling pathways.
1. Palmatine hydrochloride has hepatoprotective action.
2. Palmatine hydrochloride shows bactericidal activity.
3. Palmatine hydrochloride has uterine contractant activity.
4. Palmatine hydrochloride shows antiarrhythmic, inotropic, adrenocorticotropic, anticholinesterase and analgesic effects.
1. Liquiritigenin has a choleretic effect.
2. Liquiritigenin possesses anti-inflammatory, antihyperlipidemic, and antiallergic effects.
3. Liquiritigenin decreases TNBS-induced phosphorylation of IKKβ, p65, and IκB-α.
4. Liquiritigenin is an estrogenic compound which acts as an agonist selective for the β-subtype of the estrogen receptor.
5. Liquiritigenin exhibits antitumour action in pituitary adenoma cells via Ras/ERKs and ROS-dependent mitochondrial signalling pathways.
6. Liquiritigenin possesses cytotoxic activity against five human cancer cell lines in vitro, inhibits the cell growth of SGC-7901 and Lovo.
1. Cinnamaldehyde has antipyretic activity.
2. Cinnamaldehyde is a sedative agent.
3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the expression of miR-27a.
4. Cinnamaldehyde induces the generation of reactive oxygen species and exerts vasodilator and anticancer effects.
5. Cinnamaldehyde appears to be a promising candidate as an adjuvant in combination therapy with 5-fluorouracil (5-FU) and oxaliplatin (OXA), two chemotherapeutic agents used in CRC treatment. The possible mechanisms of its action may involve the regulation of drug‑metabolizing genes.
6. Cinnamaldehyde plays a certain role in inhibiting the occurrence and progression of melanoma and its action mechanism may be manifested by inhibiting expression of VEGF and HIF-α, thus blood vessel simulation and formation of new blood vessels of melanoma cells, and growth of tumors accordingly.