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  • Bioactive Products
    Antimalaric Compound Library
    A unique collection of 32 Antimalaric natural compounds for antimalaric drug research
    Catalog No: B81 Antimalaric Compound Library
    Screening Details
    Size: 1mg/well * 32 Compounds
    2mg/well * 32 Compounds
    Catalog No. Information
    CFN99244 Ganoderiol F

    1. Ganoderiol F has anti-inflammatory activity.
    2. Ganoderiol F shows cytotoxic and anti-HIV activities.
    3. Ganoderiol F induces growth arrest of cancer cell lines HepG2, Huh7 and K562.
    4. Ganoderiol F inhibits activity of topoisomerases in vitro.
    5. Ganoderiol F inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM.
    CFN99412 9-Hydroxy-13E-labden-15-oic acid

    CFN99436 Shikimic acid

    1. Shikimic acid plays a pivotal role as a key intermediate in the shikimate pathway toward the synthesis of several aromatic amino acids and a variety of secondary metabolites in plants, fungi, and microorganisms.
    2. Shikimic acid has great potential for the design and synthesis of enzyme inhibitors which may selectively block specific enzyme-catalysed transformations along this pathway.
    3. Shikimate can be used to synthesise (6S)-6-Fluoroshikimic acid, an antibiotic which inhibits the aromatic biosynthetic pathway.
    CFN99575 Licochalcone A

    1. Licochalcone A exhibits potent antimalarial activity via and might be developed into a new antimalarial drug.
    2. Licochalcone A had anti-tumor activity in all cell lines tested and enhanced the effect of paclitaxel and vinblastine chemotherapy.
    3.Licochalcone A induced apoptosis in MCF-7 and HL-60 cell lines, as demonstrated by cleavage of PARP, the substrate of ICE-like proteases.
    4. Licochalcone A exhibits a strong antileishmanial activity ,that appropriate substituted chalcones might be a new class of antileishmanial drugs.
    CFN99622 Chrysosplenol D

    1. Chrysosplenol D inhibited inflammation in vitro and in vivo.
    2. Chrysosplenol D is important antibiotics and antimalarials.
    3. Chrysosplenol D suppressed LPS-induced release of IL-1 beta, IL-6 and MCP-1, inhibited cell migration, and reduced LPS-induced IκB and c-JUN phosphorylation in Raw264.7 cells.