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Bioactive Products
Antimalaric Compound Library
A unique collection of 32 Antimalaric natural compounds for antimalaric drug research
Catalog No: B81 Antimalaric Compound Library
Screening Details
Size: 1mg/well * 32 Compounds
2mg/well * 32 Compounds
Cat. No. Information
CFN96394 Khellactone

Khellactone shows antitumor activity,it can suppress the growth of NCI-H460 tumor cells. (+)-4'-cis-Khellactone and (+)-3'-cis-khellactone have antiplasmodial activities, they show notable inhibitory activity against -sensitive strains of with IC(50) values from 1.5 and 2.4 microM.
CFN96468 Uncarinic acid E

Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resulting in cytochrome c release from the mitochondria. A mixture of uncarinic acid E and 27-O-p-(E)-coumaroyloxyursolic acid exhibits antiplasmodial activity, with the IC50 value of 2.9 microg/ml.