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    Cratoxylone
    Cratoxylone
    Information
    CAS No. 149155-01-1 Price
    Catalog No.CFN93577Purity>=98%
    Molecular Weight428.5Type of CompoundXanthones
    FormulaC24H28O7Physical DescriptionYellow powder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)
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    Cratoxylone Description
    Source: The fruits of Garcinia mangostana
    Biological Activity or Inhibitors: 1. Cratoxylone exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with the IC₅₀ value belows 3 uM.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.3337 mL 11.6686 mL 23.3372 mL 46.6744 mL 58.3431 mL
    5 mM 0.4667 mL 2.3337 mL 4.6674 mL 9.3349 mL 11.6686 mL
    10 mM 0.2334 mL 1.1669 mL 2.3337 mL 4.6674 mL 5.8343 mL
    50 mM 0.0467 mL 0.2334 mL 0.4667 mL 0.9335 mL 1.1669 mL
    100 mM 0.0233 mL 0.1167 mL 0.2334 mL 0.4667 mL 0.5834 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Cratoxylone References Information
    Citation [1]

    Planta Med. 2011 Mar;77(4):377-9.

    Antiplasmodial constituents from the fruit pericarp of Pentadesma butyracea.[Pubmed: 20927694 ]
    Bioassay-guided fractionation of the fruit pericarp of Pentadesma butyracea, using the antiplasmodial test, led to the isolation of a new xanthone, named pentadexanthone (1), together with six known compounds: Cratoxylone (2), α-mangostin (3), 1,3,5-trihydroxy-2-methoxyxanthone (4), garcinone E (5), (-)-epicathechin (6), and lupeol (7). The structure of 1 was elucidated by spectroscopic data analysis. An antiplasmodial assay was performed with the isolates, in which compounds 1- 3 and 5 exhibited potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC₅₀ values below 3 μM.