Bioactive Products
| A unique collection of 71 Anti-hyperlipidemic natural compounds with biological activity of Anti-hyperlipidemic | ||
| Catalog No: | Bb134 | Anti-hyperlipidemic Compound Library Screening Details |
| Size: | 1mg/well * 71 Compounds 2mg/well * 71 Compounds | |
| Cat. No. | Information |
| CFN98928 | Costunolide Costunolide has antipyretic, anti-inflammatory, anti-oxidant, anti-carcinogenic and anti-fungal activities, it possesses normo-glycemic and hypolipidemic activity. Costunolide inhibits RANKL-induced osteoclast differentiation by suppressing RANKL-mediated c-Fos transcriptional activity; it inhibits IL-1beta gene expression by blocking the activation of MAPKs and DNA binding of AP-1; it also induces the ROS-mediated mitochondrial permeability transition and resultant cytochrome c release, |
| CFN97007 | Soyasapogenol B Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2. |
| CFN97009 | beta-Amyrin palmitate Beta-Amyrin palmitate may release norepinephrine from newly synthesized pools, and thus, it may activate noradrenergic activity. Beta-Amyrin palmitate, like mianserin and imipramine, reduces the duration of immobility of mice significantly in a dose-dependent manner (5, 10 and 20 mg kg-1); (1)Beta-Amyrin palmitate or mianserin elicits a dose-related reduction in locomotor activity of mice and antagonizes locomotor stimulation induced by methamphetamine, imipramine increases locomotor activity and potentiates methamphetamine-induced hyperactivity; (2)Beta-Amyrin palmitate shows no effect on reserpine-induced hypothermia, whilst mianserin (10 mg kg-1) and imipramine (10 and 20 mg kg-1) antagonizes the reserpine-induced effect; (3)Beta-amyrin palmitate has similar properties in some respects to mianserin and might possess a sedative action. |
| CFN97034 | Sesamin Sesamin has antifibrotic, cholesterol-lowering, anti-cancer, antioxidative, neuroprotective, anti-atherosclerosis, anti-inflammatory properties, it also might be beneficial in the prevention of hypertension and stroke. Sesamin attenuates intercellular cell adhesion molecule-1 expression in vitro in TNF-α-treated human aortic endothelial cells and in vivo in apolipoprotein-E-deficient mice.Sesamin also can protect β-cells from damage caused by AGEs through suppressing NADPH oxidase-mediated oxidative stress. |
| CFN97148 | Catalposide Catalposide possesses antioxidant, anti-apoptotic, anti-microbial, anti-tumoral, and anti-inflammatory properties. Catalposide is a potent inducer of HO-1 and HO-1 induction is responsible for the catalposide-mediated cytoprotection against oxidative damage.Catalposide is a natural agonistic ligand of peroxisome proliferator-activated receptor-α, is hypolipidemic by activation of PPARαvia a ligand-mediated mechanism that modulates the expression of in lipid metabolism genes in hepatocytes. |
