Bioactive Products
| A unique collection of 71 Anti-hyperlipidemic natural compounds with biological activity of Anti-hyperlipidemic | ||
| Catalog No: | Bb134 | Anti-hyperlipidemic Compound Library Screening Details |
| Size: | 1mg/well * 71 Compounds 2mg/well * 71 Compounds | |
| Cat. No. | Information |
| CFN97259 | Ursolic acid Ursolic acid is a potential PPARγagonist, which has anti-tumor, chemopreventive, hepatoprotective, anti-inflammatory, antioxidant, antidepressant-like, antimicrobial activities, and anti-asthmatic effects. Ursolic acid also has antihyperlipidemic, hypoglycemic and direct cardiac effect, its antihypertensive effect is attributed to its potent diuretic-natriuretic-saluretic activity. Ursolic acid regulates NF-κB, VEGF, COX-2, Nrf2, ARE, IL-5, IL-13, IL-17and MAPK signaling pathways. |
| CFN97326 | Stigmasterol Stigmasterol is used as a precursor in the manufacture of synthetic progesterone, it is an antagonist of the bile acid nuclear receptor FXR, which has anti-inflammatory, thyroid inhibitory, cholesterol-lowering, antiperoxidative and hypoglycemic effects; it has indicated that stigmasterol may be useful in prevention of certain cancers, including ovarian, prostate, breast, and colon cancers. Stigmasterol inhibits the NF-kappaB pathway. |
| CFN97503 | Umbelliferone Umbelliferone is a competitive inhibitor of alkaline phosphatase. It is a fluorescing compound used as a sunscreen agent and shows good inhibitions of DPPH, hydroxyl, superoxide anion and ABTS radicals with antinociceptive, anti-inflammatory, anti-hyperglycaemic, anti-allergic, molluscicidal and anti-tumor activities. Umbelliferone has stimulatory effect on adipocyte differentiation likely occurs through up-regulation of adipogenic transcription factors and downstream adipocyte-specific gene expression. |
| CFN90170 | Theaflavin-3-gallate Theaflavin-3-gallate has anticancer and apoptotic effects in non-small cell lung carcinoma, it acts as prooxidants and induce oxidative stress, with carcinoma cells more sensitive than normal fibroblasts. Theaflavin-3-gallate can play a role in decreased intestinal cholesterol absorption via inhibition of micelle formation. |
| CFN90198 | Alisol A 24-acetate Alisol A 24-acetate has antibacterial activity, it also has anti-complement activity against the classical pathway of the complement system with IC50 values of 130 microM. Alisol A 24-acetate can effectively prevent bone loss in ovariectomized (OVX) mice, and that it can be considered a potential therapeutic for the treatment of postmenopausal osteoporosis. |
