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Bioactive Products
Anti-inflammatory Compound Library
A unique collection of 552 Anti-inflammatory natural compound library for Anti-inflammatory screening and New Anti-inflammatory drug research
Catalog No: B72a26 Anti-inflammatory Compound Library
Screening Details
Size: 1mg/well * 552 Compounds
2mg/well * 552 Compounds
Cat. No. Information
CFN98134 Platycodin D

Platycodon D shows antinociceptive, and anti-inflammatory activities, it can induce autophagy in NCI-H460 and A549 cells through inhibiting PI3K/Akt/mTOR signaling pathway and activating JNK and p38 MAPK signaling pathways. Platycodon D can inhibit migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathways. Platycodin D is also a potent adjuvant of specific cellular and humoral immune responses against recombinant hepatitis B antigen.
CFN98139 Praeruptorin A

Praeruptorin A exerts neuroprotective, anti-osteoclastogenic, anti-inflammatory, distinct relaxant effects, it is beneficial to facilitate nestin expression in myocarditis,and suitable in treatment of early myocarditis. Praeruptorin A can significantly up-regulate UGT1A1 expression in HepG2 cells partially via the CAR-mediated pathway. Praeruptorin A inhibited p38/Akt-c-Fos-NFATc1 signaling and PLCĪ³-independent Ca2+ oscillation.
CFN98314 Salirepin

Salirepin has anti-inflammatory activity, it can significantly inhibit lipopolysaccharide- induced nitric oxide production in BV2 microglia.
CFN98141 (+)-Praeruptorin A

(+)-Praeruptorin A exerts distinct relaxant effects on isolated rat aorta rings, which may be mainly attributed to nitric oxide synthesis catalyzed by endothelial nitric oxide synthase.
CFN98142 Praeruptorin D

Praeruptorin D exhibits antitumor and anti-inflammatory activities, it protects mice from hydrochloric acid (HCl)-induced lung injury by inhibiting PMNs influx, IL-6 release and protein exudation. Praeruptorin D can significantly up-regulate CYP3A4 expression and activity via the Pregnane X receptor (PXR)-mediated pathway.