Bioactive Products
Cat. No. | Information |
CFN92843 | Corynantheine Corynantheine shows pronounced activity against Leishmania major promastigotes (IC50 at the micromolar level) but no significant in vitro antiplasmodial activity (against chloroquinesensitive Plasmodium falciparum). |
CFN92844 | Dihydrocorynantheine Dihydrocorynantheine shows pronounced activity against Leishmania major promastigotes (IC50 at the micromolar level) but no significant in vitro antiplasmodial activity (against chloroquinesensitive Plasmodium falciparum). Dihydrocorynantheine exhibits significant vasodilating activity against phenylephrine-induced contraction in rat thoracic aorta rings (IC(50) = 6.73 μg/mL), it also shows weak inhibitory action on KCl-induced contraction. |
CFN92859 | Coronaridine Coronaridine is an antitumor agent. Coronaridine congeners inhibit hα3β4 AChRs by blocking the ion channel's lumen and probably by additional negative allosteric mechanisms by interacting with a series of non-luminal sites. |
CFN90588 | Primin Primin has antimycobacterial, and strong antineoplastic actions. Primin has potent activity against Trypanosoma brucei rhodesiense (IC50 0.144 microM) and Leishmania donovani (IC50 0.711 microM), and low cytotoxicity (IC50 15.4 microM) on mammalian cells; it could serve as a lead compound for the rational design of more potent and less toxic antiprotozoal agents. |
CFN90622 | Valechlorine Valeranone shows antileishmanial and cytotoxic activity. |