Bioactive Products
| A unique collection of 674 anticancer natural compounds for high throughput screening (HTS) and New anticancer drug research | ||
| Catalog No: | B91 | Anticancer Compound Library Screening Details |
| Size: | 1mg/well * 674 Compounds 2mg/well * 674 Compounds | |
| Cat. No. | Information |
| CFN98429 | Quercetin 3,4'-dimethyl ether Quercetin 3,4’-dimethyl ether shows anti-lipid peroxidation activity (IC 50 values of 0.3 uM), it also shows anti-inflammatory activity. Quercetin 3,4’-dimethyl ether could be useful in the development of novel anticancer agents, it has high cytotoxic against leukemia cells, it induces cell death is mediated by an intrinsic dependent apoptotic event involving mitochondria and MAPKs, and through a mechanism independent of the generation of reactive oxygen species. |
| CFN98431 | Hypophyllanthin Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice. Hypophyllanthin can modulate the vascular tension via the endothelium-independent mechanisms, it can directly inhibit P-gp activity and does not interfere with MRP2 activity, it may reversibly inhibit P-gp function. Hypophyllanthin offers a promising means for treatment of chronic muscle pain. Hypophyllanthin also has estrogenic properties against carbofuran induced toxicity in female rats. |
| CFN98501 | Tigogenin Tigogenin is one of steroidal sapogenins which is widely used for synthesizing steroid drugs. It might have protective effect on bone and be helpful in preventing the development of osteoporosis.Tigogenin induces apoptosis, associated with overexpression of COX-2 correlated with overproduction of endogenous PGE2. Tigogenin inhibited of PPARgamma and via p38 MAPK pathway. |
| CFN98509 | Decursin Decursin has antiepileptic, hepatoprotective, anti-cancer, anti-inflammatory, and anti-amnesic activities, it is a novel candidate for inhibition of VEGF-induced angiogenesis. Decursin inhibited the TGF-β1 induced NOX activation and Smad signaling, it inhibited the PKCα, MAPK and NF-κB pathways. Decursin is also a novel inhibitor of NF-kappaB activation in signaling induced by TLR ligands and cytokines. |
| CFN98434 | Abieta-8,11,13-triene-7,15,18-triol Abieta-8,11,13-triene-7alpha,15,18-triol,7alpha,8alpha,13beta,14beta-diepoxyabietan-18-oic acid, and 18-nor-abieta-8,11,13-triene-4alpha,7alpha,15-triol may have inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), they may as a primary screening for antitumor promotors. |
